Sökning: "mucus layer"

Visar resultat 11 - 15 av 45 avhandlingar innehållade orden mucus layer.

  1. 11. Study of the colonic mucus layer by mass spectrometry

    Författare :Sjoerd van der Post; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MUC2; mucin; intestine; proteomics; mass spectrometry;

    Sammanfattning : The mucus covering our internal mucosal surfaces is a part of the innate immune system, and the first line of defense against microbial challenges. The need of an efficient defense system is especially important in the lower parts of the digestive tract where the microbiota reaches its highest density. LÄS MER

  3. 12. Acid transport through gastric mucus : A study in vivo in rats and mice

    Författare :Mia Phillipson; Lena Holm; Henrik Sjövall; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Physiology; gastric acid; pH-sensitive microelectrode; mucus; mucosal blood flow; nitric oxide; intravital microscopy; laser Doppler flowmetry; Fysiologi; Physiology; Fysiologi; Physiology; fysiologi;

    Sammanfattning : The gastric mucosa is frequently exposed to endogenously secreted hydrochloric acid of high acidity. Gastric mucosal defense mechanisms are arranged at different levels of the gastric mucosa and must work in unison to maintain its integrity. LÄS MER

  4. 13. The mucus layer and other barriers to intestinal drug absorption

    Författare :Agneta Wikman Larhed; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Pharmacy; FARMACI; PHARMACY; FARMACI; galenisk farmaci; Pharmaceutics;

    Sammanfattning : The extraepithelial mucus layer acts as a barrier to the absorption and diffusion of drugs. Three in vitro models have been used for studies of this and other intestinal barriers to drug transport. A drug absorption model based on monolayers of the mucus-producing human intestinal goblet HT29-H cell line was developed. LÄS MER

  5. 14. Intestinal mucins 'soluble and insoluble problems'

    Författare :Annkatrin Herrmann; Institutionen för experimentell medicinsk vetenskap; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; colorectal carcinoma; pulse labelling; organ culture; glycopeptide; small intestine; colon; glycoprotein complex; insoluble; muc2; MUC2; Mucin; mucus; carbohydrate; oligosaccharide.; Gastro-enterology; Gastroenterologi;

    Sammanfattning : Highly glycosylated glycoproteins – mucins – are the major constituents of the mucus layer and glycocalyx that cover mucosal surfaces. Twelve human mucin genes have been identified, and the mucins may be divided into those that are membraneassociated and those that are secreted. LÄS MER

  7. 15. Effect of hydration on thermodynamic, rheological and structural properties of mucin

    Författare :Yana Znamenskaya; Malmö högskola; []
    Nyckelord :mucous gel; mucus; mucin; PGM; BSM; BSM chitosan multilayers; hydration; water sorption isotherm; relative humidity; water activity; bound water; enthalpy of hydration of biopolymer; glass transition; rheology; phase diagram; fiber-like structure; dumbbell-like structure; sorption calorimetry; DSC; QCM-D; SAXS; AFM;

    Sammanfattning : Mucus, an adherent hydrated layer covering the epithelium, is found in all internal tracts of the body and plays an important role in animal and human life. One of the essential functions of mucus is protection of tissues against dehydration. LÄS MER