Sökning: "medical gene technology"

Visar resultat 26 - 30 av 120 avhandlingar innehållade orden medical gene technology.

1. 26. Genetic Sex Differences in Early Human Neuronal Development : An Investigation in Embryo Tissue and Embryonic Stem Cells

   Författare :Philipp Pottmeier; Elena Jazin; Armin Raznahan; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; sex chromosome; gametolog; x y homolog; male; female; sex differences; sex bias; embryonic stem cells; neurodevelopment; neuronal differentiation; neural stem cells; genetics; neurodevelopmental disorders; Biology with specialization in Evolutionary Organismal Biology; Biologi med inriktning mot evolutionär organismbiologi; Neuroscience; Neurovetenskap; Medicinsk genetik; Medical Genetics;

   Sammanfattning : Sex differences in the human body affect many different organs and tissues, some of them have an effect on the human brain and its development. In the developing nervous system, sex differences can bias the number or functionality of neurons, glial cells or synapses. As a result, neural networks might develop with a sex-specific bias. LÄS MER

3. 27. Methods development for metaproteomics-guided bioprospecting of novel enzymes

   Författare :Jutta Speda; Martin Karlsson; Nalle Jonsson; Antonius Van Maris; Linköpings universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

   Sammanfattning : Industrial biotechnology has been announced by several organizations and governments as a key enabling technology for the enhanced economic growth in a low-carbon and knowledge-based bioeconomy. An important goal to promote an environment friendly and sustainable industrial biotechnology is the discovery of new enzymes. LÄS MER

4. 28. Image Processing, Machine Learning and Visualization for Tissue Analysis

   Författare :Leslie Solorzano; Carolina Wählby; Alexandru Cristian Telea; Uppsala universitet; []
   Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Image processing; data analysis; machine learning; visualization; microscopy; Bioinformatics; Bioinformatik;

   Sammanfattning : Knowledge discovery for understanding mechanisms of disease requires the integration of multiple sources of data collected at various magnifications and by different imaging techniques. Using spatial information, we can build maps of tissue and cells in which it is possible to extract, e.g. LÄS MER

5. 29. Molecular Aspects of Transthyretin Amyloid Disease

   Författare :Karin Sörgjerd; Per Hammarström; Joel Buxbaum; Linköpings universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Amyloid; apoptosis; BiP; chaperone; misfolding; oligomer; transthyretin; Biochemistry; Biokemi;

   Sammanfattning : This thesis was made to get a deeper understanding of how chaperones interact with unstable, aggregation prone, misfolded proteins involved in human disease. Over the last two decades, there has been much focus on misfolding diseases within the fields of biochemistry and molecular biotechnology research. LÄS MER

7. 30. Chromosome rearrangements do not prevent gene flow in the common shrew, Sorex araneus : Analysis of two chromosomal hybrid zones in Sweden

   Författare :Yolanda Narain; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Genetics; Genetik; Clinical genetics; Klinisk genetik; Genetics; genetik; NATURAL SCIENCES;

   Sammanfattning : Two chromosomal hybrid zones of the common shrew, Sorex araneus, have been investigated: the Hällefors-Uppsala hybrid zone in central Sweden and the Abisko-Sidensjö hybrid zone in northern Sweden. The Hällefors (Hä) and Uppsala (Up) chromosome races consisted of biarmed autosomes only (2nA=18), and differed in the Robertsonian fusions of two arms, ko, pq, and kp, oq, respectively. LÄS MER