Sökning: "intradermal injection"

Visar resultat 6 - 10 av 23 avhandlingar innehållade orden intradermal injection.

  1. 6. Dynamic mechanical allodynia in peripheral neuropathic pain : psychological observations

    Författare :Monika Samuelsson; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Dynamic mechanical allodynia; Brush-evoked allodynia; Brush-evoked pain; Neuropathic pain; Pain descriptors; Repeatability; Human pain model; Capsaicin; Psychophysical observations;

    Sammanfattning : Introduction and aim: Pain due to a light moving mechanical stimulus, dynamic mechanical allodynia, is a protruding symptom/sign in subgroups of patients with peripheral neuropathic pain and frequently as troublesome as spontaneous ongoing pain. The objective of this thesis was to survey psychophysical details of dynamic mechanical allodynia using a novel semi-quantitative method. LÄS MER

  3. 7. In vivo bioluminescence imaging in preclinical trials of genetic vaccines

    Författare :Stefan Petkov; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : DNA immunization is a rapidly developing vaccine platform for infectious diseases, cancer and allergies. The efficiency of DNA vaccination is largely determined by the efficiency of delivery and subsequent expression of genes encoding microbial and tumor antigens or allergens in the cells of vaccine recipients. LÄS MER

  4. 8. Superparamagnetic iron oxide nanoparticles (SPIONs) as a multimodality imaging probe for sentinel nodes : Design and Preclinical Evaluation

    Författare :Renata Madru; Lund Medicinsk strålningsfysik; []
    Nyckelord :iron oxide; nanoparticles; SPIONs; PET-MRI; SPECT-MRI; SPECT-MRI- optical imaging; sentinel lymph node; SNL;

    Sammanfattning : Breast cancer and malignant melanoma disseminate through the lymphatic system and the first metastases arise in one or two regional, sentinel lymph nodes (SLNs) draining the primary tumour site. Therefore, identification and characterization of the SLNs is of major importance for cancer staging and for choice of therapy in patients. LÄS MER

  5. 9. Strategies to enhance the potency of HIV-1 DNA vaccines

    Författare :David Hallengärd; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Despite 30 years of intense research on HIV/AIDS, we have yet to arrive at a prophylactic vaccine that confers complete protection. This mission is complicated by the virus’s vast genetic variability and its ability to mask the targets for neutralizing antibodies. LÄS MER

  7. 10. Specifity and genetic control of B cell reactivity in experimental arthritis

    Författare :Patrik Wernhoff; Immunologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; serologi; transplantation; Genetics; cytogenetics; Genetik; cytogenetik; Immunologi; Autoimmunity B-cell response Epitope Genetics Linkage Analysis; Immunology; serology;

    Sammanfattning : Collagen-induced arthritis (CIA) and pristane-induced arthritis (PIA) are animal models for human rheumatoid arthritis (RA), and can be induced in susceptible mouse and rat strains. CIA is induced by immunization of type II collagen (CII), a cartilage specific protein together with Freund’s adjuvant. LÄS MER