Sökning: "Human pain model"

Visar resultat 1 - 5 av 62 avhandlingar innehållade orden Human pain model.

  1. 1. Human experimental pain models : methodological and analgesic studies

    Författare :Helène Schulte; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Pain; human volunteers; pain threshold; hyperalgesia; opioids; ketamine;

    Sammanfattning : Pain is an important clinical issue with great impact on society and individuals' well being. It is well established that sensory abnormalities induced by tissue trauma and inflammation are clinically important in various acute and chronic pain conditions. LÄS MER

  3. 2. Influences of paratendinous innervation and non-neuronal substance P in tendinopathy : studies on human tendon tissue and an experimental model of Achilles tendinopathy

    Författare :Gustav Andersson; Patrik Danielson; Sture Forsgren; Håkan Alfredson; David A. Hart; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Achilles tendon; tendinopathy; tendinosis; paratenon; innervation; substance P; neuropeptides; neurokinin-1 receptor; Anatomy; Anatomi; anatomi; Human Anatomy;

    Sammanfattning : Pain of the musculoskeletal system is one of the most common reasons for people seeking medical attention, and is also one of the major factors that prevent patients from working. Chronic tendon pain, tendinopathy, affects millions of workers world-wide, and the Achilles tendon is an important structure often afflicted by this condition. LÄS MER

  4. 3. Applying proteomics and metabolomics for studying human skeletal muscle with a focus on chronic trapezius myalgia

    Författare :Jenny Hadrévi; Albert Crenshaw; Fatima Pedrosa-Domellöf; Fredrik Hellström; Bijar Ghafouri; Mary F Barbe; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Trapezius myalgia; proteomics; 2D-DIGE; metabolomics; microdialysate; biopsies; anatomi; Human Anatomy;

    Sammanfattning : Work related musculoskeletal disorders are the dominating causes of reported ill-health in industrialized countries. These chronic pain conditions are one of the most costly public health problems in Europe and North America. LÄS MER

  5. 4. External otitis and its treatment : is a group III steroid without antibiotics sufficent therapy? Experimental and clinical studies

    Författare :Per Emgård; Sten Hellström; Dan Bagger-sjöbäck; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Medicine; external otitis; external auditory canal EAC ; animal model; treatment; betamethasone; hydrocortisone; antibiotics; human study; Pseudomonas aeruginosa; Candida albicans.; Medicin; Dermatology and venerology; clinical genetics; internal medicine; Dermatologi och venerologi; klinisk genetik; invärtesmedicin; Oto-Rhino-Laryngology; oto-rhino-laryngologi;

    Sammanfattning : ABSTRACT External otitis and its treatment. Is a group III steroid without antibiotics sufficient therapy? – Experimental and clinical studies Per Emgård, Department of Otorhinolaryngology, University of Umeå and Ystad Hospital, Umeå and Ystad, Sweden External otitis is one of the most common ear, nose and throat (ENT) diagnoses in out-patient clinics. LÄS MER

  7. 5. Hemorphins and endomorphins

    Författare :Katarina Sanderson Nydahl; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Pharmaceutical biosciences; Hemorphins; endomorphins; opioid receptors; peptide metabolism; neurogenic inflammation; pain; Farmaceutisk biovetenskap; Biopharmacy; Biofarmaci; biologisk beroendeforskning; Biological Research on Drug Dependence;

    Sammanfattning : In this thesis, two newly discovered endogenous opioid peptide families, the hemorphins and endomorphins, are investigated with emphasis on modulation of pain and inflammation. In addition, the presence of hemorphins in human biological fluids as well as the in vitro and in vivo processing ofLVV-hemorphin-7 in blood and brain is investigated. LÄS MER