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Visar resultat 1 - 5 av 23 avhandlingar som matchar ovanstående sökkriterier.

  1. 1. A Fully Integrated Microneedle-based Transdermal Drug Delivery System

    Författare :Niclas Roxhed; Göran Stemme; Mark G. Allen; KTH; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Microneedle; Transdermal; Intradermal; Drug delivery; DRIE; MEMS; Microsystem; Medical technology; Medicinsk teknik;

    Sammanfattning : Patch-based transdermal drug delivery offers a convenient way to administer drugs without the drawbacks of standard hypodermic injections relating to issues such as patient acceptability and injection safety. However, conventional transdermal drug delivery is limited to therapeutics where the drug can diffuse across the skin barrier. LÄS MER

  3. 2. Study of pruritus in psoriasis vulgaris : role of tachykinins

    Författare :Beni Amatya; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Itch; pruritus; psoriasis; tachykinin; questionnaire; focus group; intradermal injection;

    Sammanfattning : Pruritus has not been considered as the most important symptom of psoriasis. In the present thesis various methodologies have been used to investigate this symptom in psoriasis. The focus groups created a proper atmosphere for discussion on different aspects of pruritus in psoriasis. Pruritus was most common on the lower back and legs. LÄS MER

  4. 3. Ropivacaine : An experimental and clinical study with special reference to analgesic, circulatory and antiinflammatory effects

    Författare :Ingemar Cederholm; Linköpings universitet; []
    Nyckelord :MEDICINE; MEDICIN;

    Sammanfattning : Aims of the study: 1. to compare ropivacaine, a new long-acting amino-amide local anaesthetic drug, and bupivacaine (with/without adrenaline) concerning dermal analgesia and local vascular effects, 2. to design a suitable test procedure to evaluate changes in skin blood flow after intradermal injection of local anaesthetics, 3. LÄS MER

  5. 4. Cutaneous resistance against Francisella tularensis

    Författare :Stephan Stenmark; Mikael Rhen; Umeå universitet; []
    Nyckelord :tularemia; Francisella tularensis; skin; protection; cytokines; T-cells; B-cells; specific antibodies; Infectious Diseases; infektionssjukdomar;

    Sammanfattning : Francisella tularensis, the causative agent of tularemia, is a potent pathogen in humans and other mammals. The ulceroglandular form of the disease is the most common expression in humans with a clinical picture characterized by a skin ulcer, enlarged regional lymph nodes and fever. LÄS MER

  7. 5. Immune mechanisms that determine the quality of antibody responses to vaccines

    Författare :Gustaf Lindgren; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Effective vaccines for many dangerous infectious diseases are still lacking. An improved understanding of the mechanisms that determine the quality of vaccine responses is essential to guide future attempts to design effective vaccines. LÄS MER