Sökning: "insulin response"

Visar resultat 6 - 10 av 462 avhandlingar innehållade orden insulin response.

  1. 6. Insulin resistance in skeletal muscle. With special reference to interstitial insulin and glycerol

    Författare :Mikaela Sjöstrand; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; insulin resistance; skeletal muscle; microdialysis; interstitial insulin; interstitial glycerol;

    Sammanfattning : Insulin resistance is a central feature of type 2 diabetes and obesity and is associated with cardiovascular disease. In insulin-resistant muscle, the insulin-mediated glucose uptake is decreased.The delivery of insulin to the interstitial fluid of human skeletal muscle has previously not been investigated. LÄS MER

  3. 7. Pathogenesis of type 2 diabetes -role of defects in insulin secretion and insulin sensitivity

    Författare :Devjit Tripathy; Malmö Institutionen för kliniska vetenskaper; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; diabetology; Endokrinologi; sekretion; diabetologi; Endocrinology; secreting systems; Calpain 10 gene; genetics of type 2 diabetes; MODY; Endogenous glucose production; Disposition index; Botnia clamp; IGT; IFG; HOMA; insulin sensitivity; insulin secretion;

    Sammanfattning : Type 2 diabetes is characterised by defects in insulin sensitivity, insulin secretion and increased endogenous glucose production. The relative contribution of each of these defects remains controversial. LÄS MER

  4. 8. Glucose- and hypoxia-regulated insulin gene expression

    Författare :Linda Tillmar; Jens Höiriis Nielsen; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Cell biology; islet; beta-cell; insulin; mRNA stability; PTB; glucose; hypoxia; mTOR; p70s6k; ceramide; redox; ROS; Cellbiologi; Cell biology; Cellbiologi; medicinsk cellbiologi; Medical Cell Biology;

    Sammanfattning : Although extensively studied, there are still many unanswered questions regarding the exact regulation of insulin gene expression. This is important to further investigate since it will hopefully help us understand the pathophysiology of some types of diabetes. LÄS MER

  5. 9. New modifiers of insulin signalling identified by interaction screens with ASNA-1 in C. elegans

    Författare :Balasubramanian Natarajan; Peter Naredi; Richard Padgett; Umeå universitet; []
    Nyckelord :Insulin; C. elegans; ASNA1; Cisplatin; GRP94; unfolded protein response; SMN1; Developmental Biology; miljömedicinsk utvecklingsbiologi;

    Sammanfattning : Background: Insulin is a hormone released by the pancreatic beta cells in response to elevated levels of nutrients in the blood. Insulin triggers the uptake of glucose, fatty acids and amino acids into the liver, adipose tissue and muscles. LÄS MER

  7. 10. Nutritional improvement by lactic acid fermentation : studies on iron availability and postprandial glucose/insulin response

    Författare :Sharon Wang Bergqvist; Chalmers tekniska högskola; []
    Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; insulin response; iron absorption; mineral avaliability; ferrous iron; blood glucose; lactic acid fermentation; caco-2 cells;

    Sammanfattning : .... LÄS MER