Sökning: "C. elegans"

Visar resultat 1 - 5 av 66 avhandlingar innehållade orden C. elegans.

  1. 1. Regulation of energy balance in Caenorhabditis elegans 

    Författare :Ming Sheng; Simon Tuck; Lars Nilsson; Carina Holmberg-Still; Umeå universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; C.elegans; fat metabolism; S6 Kinase; FT-IR; molekylär medicin genetik och patologi ; molecular medicine  genetics and pathology ;

    Sammanfattning : Obesity is a medical condition in which excess body fat has been accumulated. It is most commonly caused by imbalance between energy intake and energy expenditure (lack of physical activity and lower metabolic rate, etc.). LÄS MER

  2. 2. Hyperoxia avoidance and aggregation behavior in C. elegans

    Författare :Annelie Persson; Göteborgs universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; c. elegans; aggregation;

    Sammanfattning : Living in the soil, C. elegans can move in three dimensions in search for food. To navigate, it partly uses oxygen levels as a description of its habitat. Oxygen tension may indicate presence of microbial food and location with respect to the surface, where oxygen is 21%. LÄS MER

  3. 3. Studies on lipid transport and extracellular vesicle production in Caenorhabditis elegans ciliated neurons

    Författare :Shapour Rahmani; Simon Tuck; Jonathan D. Gilthorpe; Anders Olsen; Umeå universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; C. elegans; cilia; extracellular vesicles; tat; phospholipid translocase; P4-family ATPase;

    Sammanfattning : The cilium is a protrusion of cell membrane. Both the protein and lipid contents of cilia are different from those of other parts of the cell membrane. While the transport of proteins into and out of cilia has been intensively studied, much less is known about how the lipid content of ciliary membranes is regulated. LÄS MER

  4. 4. ASNA1 and cisplatin resistance : studies in C. elegans and in human tumor cells

    Författare :Oskar Hemmingsson; Peter Naredi; Mef Nilbert; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; ASNA1; Cisplatin; C. elegans; Drug resistance; Apoptosis; Surgery; Kirurgi; Oncology; Onkologi; Surgery; kirurgi; Oncology; onkologi; cellforskning; cell research;

    Sammanfattning : Platinum based chemotherapy is widely used to treat cancer. Cisplatin (diamminedichloroplatinum) combination treatments provide cure for metastatic testicular cancer and prolong survival for patients suffering from ovarian, head and neck, bladder and non small cell lung cancer. LÄS MER

  5. 5. A molecular exploration of sensory responses in c. elegans

    Författare :Longjun Pu; Changchun Chen; Simon Tuck; Sara I Wilson; Zhiyong Shao; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; C. elegans; sensation; CRISPR Cas9; G protein-coupled receptors; neuropeptides; acute hypoxia; pathogen; chemosensation; hydrogen sulfide; HIF-1; iron;

    Sammanfattning : Sensation provides a pivotal ability, allowing animals to survive in complex environments. The cues sensed by animals are represented by external stimuli and internal signals. However, the mechanisms mediating sensations in molecular and cellular level are still not well-studied. In this thesis, by using free-living nematodes C. LÄS MER