Sökning: "variant."

Visar resultat 1 - 5 av 987 avhandlingar innehållade ordet variant..

1. 1. Understanding Variability-Aware Analysis in Low-Maturity Variant-Rich Systems

   Författare :Mukelabai Mukelabai; Göteborgs universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Variant-rich Systems; Quality Assurance; Low Maturity Software Systems; Recommender System;

   Sammanfattning : Context: Software systems often exist in many variants to support varying stakeholder requirements, such as specific market segments or hardware constraints. Systems with many variants (a.k.a. LÄS MER

3. 2. Biology of inerleukin-7 variant isoforms

   Författare :Lalit Shirish Rane; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :;

   Sammanfattning : The interleukin-7 (IL-7) gene produces nine alternatively spliced mRNA variants. Until now, the clinical and biological significance of alternatively spliced IL-7 products has not been well defined. In this thesis, we investigated IL-7 gene alternative splicing in association with chronic inflammation and infection. LÄS MER

4. 3. Exploring genetic heterogeneity in cancer using high-throughput DNA and RNA sequencing

   Författare :Erik Fasterius; Cristina Al-Khalili Szigyarto; Mathias Uhlén; Peter-Bram ’t Hoen; KTH; []
   Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; NATURVETENSKAP; NATURAL SCIENCES; Biotechnology; bioinformatics; RNA-seq; WGS; WES; systems biology; variant analysis; single nucleotide variant; gene expression; machine learning; clustering; open source; R; bioconductor; Python; Bioteknologi; Biotechnology;

   Sammanfattning : High-throughput sequencing (HTS) technology has revolutionised the biomedical sciences, where it is used to analyse the genetic makeup and gene expression patterns of both primary patient tissue samples and models cultivated in vitro. This makes it especially useful for research on cancer, a disease that is characterised by its deadliness and genetic heterogeneity. LÄS MER

5. 4. Facilitating Feature-Oriented Quality Assurance in Low-Maturity Variant-rich Systems

   Författare :Mukelabai Mukelabai; Göteborgs universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Variant-Rich Systems; Cloned Projects; Quality Assurance; Feature Location; Test Case Reuse; Recommender System;

   Sammanfattning : Context: Many software systems exist in several variants customized for specific stakeholder requirements, such as different market segments or hardware constraints. This customization introduces a high level of complexity that renders traditional single-system quality assurance techniques inapplicable, since they need to consider variations and constraints between a system’s features—a. LÄS MER

7. 5. A Framework for Seamless Variant Management and Incremental Migration to a Software Product-Line

   Författare :Wardah Mahmood; Göteborgs universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Model Comprehension; Variability Mechanisms Process Models; Variant-rich Systems; Software Product-Line Engineering;

   Sammanfattning : Context: Software systems often need to exist in many variants in order to satisfy varying customer requirements and operate under varying software and hardware environments. These variant-rich systems are most commonly realized using cloning, a convenient approach to create new variants by reusing existing ones. LÄS MER