Sökning: "glomerular hyperfiltration"

Visar resultat 6 - 8 av 8 avhandlingar innehållade orden glomerular hyperfiltration.

  1. 6. Novel Approaches to Treatment and Prevention of Diabetic Nephropathy

    Författare :Lina Nordquist; Mats Sjöquist; Peter Bergsten; William J. Welch; Uppsala universitet; []
    Nyckelord :Physiology; Diabetes; Nephropathy; C-peptide; Microneedle; Renal; GFR; Oxygen Consumption; Reabsorption; Fysiologi;

    Sammanfattning : Several studies have reported beneficial effects of C-peptide supplementation in diabetic patients and animal models of insulinopenic diabetes. However, it is also established that good glycemic control is essential to minimize the risk of diabetes-induced complications. LÄS MER

  3. 7. The Role of Mitochondrial Uncoupling in the Development of Diabetic Nephropathy

    Författare :Malou Friederich Persson; Fredrik Palm; Richard K. Porter; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Kidney; mitochondria; Uncoupling Protein-2; Adenosine Nucleotide Transporter; uncoupling; diabetes; diabetic nephropathy; db db; dinitrophenol; Coenzyme Q10; oxygen; rats; mice; Physiology; Fysiologi; Medical Cell Biology; Medicinsk cellbiologi;

    Sammanfattning : Diabetes is closely associated with increased oxidative stress, especially originating from the mitochondria. A mechanism to reduce increased mitochondria superoxide production is to reduce the mitochondria membrane potential by releasing protons across the mitochondria membrane. LÄS MER

  4. 8. Diabetic glomerulopathy-natural history, intervention and prediction of complications

    Författare :Nina Perrin; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Type 1 diabetes; adolescents; normoalbuminuria; normotension; glomerulopathy; kidney biopsy; ambulatory blood pressure measurement; kidney function tests; risk factors; microalbuminuria; hypertension;

    Sammanfattning : Diabetes mellitus is one of the most common chronic diseases in childhood. Diabetic nephropathy (DN) is one of the threatening complications of diabetes that occurs in 30-40% of patients after 20 years duration of disease. LÄS MER