Sökning: "gene expression regulation genetics"

Visar resultat 16 - 20 av 117 avhandlingar innehållade orden gene expression regulation genetics.

  1. 16. Regulation of Drosophila Jun by phosphorylation and the ubiquitin system during eye development

    Författare :Anders Isaksson; Biologiska institutionen; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Genetics; eye development; ubiquitin; D-Jun; phosphorylation; cytogenetics; Genetik; cytogenetik;

    Sammanfattning : The goal of these studies has been to elucidate the biological relevance of post-translational modifications in the context of a living organism. The model system used is photoreceptor differentiation during development of the compound eye in the fruit fly Drosophila melanogaster. LÄS MER

  3. 17. Genetic Variation and Expression of the IRF5 Gene in Autoimmune Diseases

    Författare :Gudlaug Thora Kristjansdottir; Ann-Christine Syvänen; Lars Rönnblom; Gunnel Nordmark; Unnur Þorsteinsdóttir; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Medical genetics; Medicinsk genetik; Genetics; genetik;

    Sammanfattning : The interferon regulatory factor 5 (IRF5) gene encodes a transcription factor that plays an important role in the innate as well as in the cell-mediated immune response. The IRF5 gene has received considerable attention since it was shown to be associated with two autoimmune diseases; systemic lupus erythematosus (SLE) and rheumatoid arthritis (RA). LÄS MER

  4. 18. Genome-wide Characterization of RNA Expression and Processing

    Författare :Ammar Zaghlool; Lars Feuk; Rickard Sandberg; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; RNA sequencing; RNA splicing; RNA processing; Gene expression; Molekylär genetik; Molecular Genetics;

    Sammanfattning : The production of fully mature protein-coding transcripts is an intricate process that involves numerous regulation steps. The complexity of these steps provides the means for multilayered control of gene expression. LÄS MER

  5. 19. Monogenic Traits Associated with Structural Variants in Chicken and Horse : Allelic and Phenotypic Diversity of Visually Appealing Traits

    Författare :Freyja Imsland; Leif Andersson; Gabriella Lindgren; Kerstin Lindblad-Toh; Eiríkur Steingrímsson; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; LANTBRUKSVETENSKAPER; AGRICULTURAL SCIENCES; Structural variation; Pigmentation; Domestication; Equids; MNR2; CCDC108; STX17; TBX3; Grey; Dun; non-dun; Rose-comb; Chicken; Genetic mapping; Phenotyping; Molekylär genetik; Molecular Genetics;

    Sammanfattning : Domestic animals have rich phenotypic diversity that can be explored to advance our understanding of the relationship between molecular genetics and phenotypic variation. Since the advent of second generation sequencing, it has become easier to identify structural variants and associate them with phenotypic outcomes. LÄS MER

  7. 20. BEN-solo proteins in genome architecture and function

    Författare :Malin Ueberschär; Qi Dai; Mattias Mannervik; Nicola Iovino; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; gene regulation; transcription; insulators; genome architecture; Polymerase II pausing; chromatin; Drosophila development; molekylär biovetenskap; Molecular Bioscience;

    Sammanfattning : Eukaryotic genomes are organized in a complex manner inside the nucleus of each cell. Chromatin insulators are DNA elements that help to fold the linear DNA fiber in three-dimensional space and partition regulatory gene units. LÄS MER