Sökning: "eye lens proteins"

Visar resultat 1 - 5 av 9 avhandlingar innehållade orden eye lens proteins.

  1. 1. Cystatin C in the Eye and in Specific Model Systems

    Författare :Johan Wasselius; Lund Institutionen för kliniska vetenskaper; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Ophtalmology; protein uptake; ciliary body; lens; cornea; retina; eye; Cystatin C; cathepsin B; Oftalmologi;

    Sammanfattning : It is a necessity of life to make proteins, and it is an equal necessity to degrade those proteins, to eliminate dysfunctional proteins, and leave room for new ones. The processes of protein synthesis and degradation into peptides - proteolysis - have attracted a great interest during the last decades. LÄS MER

  3. 2. A scattering study of concentrated lens protein solutions and mixtures - Towards understanding the molecular origin of presbyopia

    Författare :Saskia Bucciarelli; Fysikalisk kemi; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; scattering; eye lens; presbyopia; dynamical arrest; crowding; proteins; dynamics; crystallins;

    Sammanfattning : Healthy eye lenses are transparent and flexible, able to adapt shape in order to focus on far away and close-by objects. With age, however, this flexibility is lost, leading to a condition known as presbyopia. This vision disorder where close-by objects appear blurred commonly starts around the age of 40. LÄS MER

  4. 3. On the Phase Behaviour of Soft Matter: Understanding Complex Interactions via Quantitative Imaging

    Författare :Maxime Bergman; Fysikalisk kemi; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Microgels; Lysozyme; eye lens proteins; confocal microscopy; interaction potential; phase behaviour; simulations;

    Sammanfattning : The effect of microscopic colloid interactions on the resultant macroscopic phase behaviour is a frequently studied topic in soft matter resarch, and lies at the heart of this thesis. Key structural and dynamic properties of colloidal model systems across liquid-solid transitions are tracked using optical imaging techniques. LÄS MER

  5. 4. Protein-Protein Interactions in Human Aquaporin Regulation

    Författare :Jennifer Virginia Roche; Biokemi och Strukturbiologi; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Membrane proteins; Human Aquaporins; water channels; Protein-protein interaction; Regulation; AQP2; AQP0; LIP5; CaM;

    Sammanfattning : Water is an essential compoment of every living orgamism and forms a major part of the human body. Regulated water transport is crucial for proper cell functioning and body homeostasis. LÄS MER

  7. 5. Molecular and epidemiological studies on eyes with pseudoexfoliation syndrome

    Författare :Amelie Botling Taube; Jonas Bergquist; Albert Alm; Eva Larsson; Hannu Uusitalo; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Pseduoexfoliation syndrome; PEX; aqueous humor; cataract; cataract surgery; lens capsule; proteomics; mass spectrometry; MS; MALDI TOF MS MS; quantitative proteomics; iTRAQ; dimethyl labeling; imaging mass spectrometry; IMS; time of flight secondary ion mass spectrometry; TOF-SIMS; crystallin; epidemiology; risk factor; Ophtalmology; Oftalmiatrik;

    Sammanfattning : Pseudoexfoliation (PEX) syndrome is an age-related condition characterized by the production and accumulation of extracellular fibrillary material in the anterior segment of the eye. PEX predisposes for several pathological conditions, such as glaucoma and complications during and after cataract surgery. LÄS MER