Sökning: "Joachim Lundahl"
Hittade 5 avhandlingar innehållade orden Joachim Lundahl.
1. T Cells and NK Cells in Coronary Artery Disease : Longitudinal and methodological studies in humans
Sammanfattning : Coronary artery disease (CAD) is the leading cause of death worldwide and most often due to atherosclerosis. Atherosclerosis is a chronic inflammatory process that involves the arteries, inclouding those that supply blood to the heart muscle. LÄS MER
2. Migration on extracellular matrix surface and infiltration into matrix - two distinguishable activities of human T cells
Sammanfattning : Migration of T-lymphocytes on a surface coated with extracellular matrix (ECM) components (two-dimensional (2-D) migration) and migration (infiltration) into a matrix (Three-dimesional (3-D) migration) are complex events and the underlying mechanisms are not yet fully understood. Here 2-D and 3-D migration were studied by use of seven leukemic T-cell lines representing discrete differentiation stages, a non-leukemic T-cell clone, and normal peripheral blood T cells. LÄS MER
3. Eosinophil Apoptosis
Sammanfattning : Apoptosis or programmed cell death is crucial for the resolution of inflammation, and phagocytosis of apoptotic cells initiates the release of actively anti-inflammatory responses from the phagocytes. Eosinophils are one of the most potent inflammatory cells in the body and is involved in a number of diseases, most commonly associated with parasitic infections and allergic diseases. LÄS MER
4. Granulocyte Adhesion to Matrix Proteins and the Effect on the Release of Granule Proteins : Development of a Simple Method and its Application in Experimental and Clinical Studies
Sammanfattning : Granulocyte adhesion and release of their granule proteins are key steps during selective accumulation of a certain cell to an inflammatory site. Eosinophils are specifically recruited to sites of allergic inflammation and parasitic infection, whereas neutrophil influx predominates in bacterial infection and rheumatoid arthritis. LÄS MER
5. Functional Role of Immune Complexes in Rheumatic and Parasitic Diseases
Sammanfattning : Immune complexes (IC) have key pathological roles in both autoimmune and infectious diseases. In this thesis functional mechanisms behind IC-driven inflammation in rheumatic diseases and tropical infections have been studied, with special focus on the contribution of autoantibodies and cytokine-inducing properties of IC. LÄS MER