Sökning: "complete screening"

Visar resultat 6 - 10 av 79 avhandlingar innehållade orden complete screening.

1. 6. Engineered Yeast as Biocatalyst for Stereoselective reductions of Dicarbonyl Compounds

   Författare :Ted Johanson; Teknisk mikrobiologi; []
   Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; chiral; screening; process optimisation; metabolic engineering; dicarbonyl; biocatalysis; yeast; bioreduction; Biotechnology; Bioteknik;

   Sammanfattning : Chiral building blocks are needed in the chemical and pharmaceutical industries for the production of fine chemicals and pharmaceuticals. The utilisation of microorganisms and enzymes to perform stereoselective reductions of carbonyl compounds is an efficient and widely applied method for the generation of chiral molecules. LÄS MER

3. 7. Health and well-being in the elderley : A prospective population- based study

   Författare :Alette-Marie Lindgren; Uppsala universitet; []
   Nyckelord :Medical sciences; epidemiology; primary health care; prevention; gerontology; housing; health; contentment; activites; loneliness; screening; poverty; mortality; MEDICIN OCH VÅRD; MEDICINE; MEDICIN; Medicine; medicin;

   Sammanfattning : The Albertina Project is an epidemiological study of the social, medical, economic and mortality situation among 9440 people, 75 years or older, living in the city of Uppsala, Sweden. Most people lived in their own home. The housing standard appeared to be satisfactory in the majority of cases. LÄS MER

4. 8. Dynamic Covalent Resolution: Applications in System Screening and Asymmetric Synthesis

   Författare :Pornrapee Vongvilai; Olof Ramström; Benjamin Miller; KTH; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; dynamic covalent kinetic combinatorial resolution; Self-screening; Transesterification; Amidation; Enzyme catalysis; Nitroaldol reaction; Secondary alcohols; Strecker reaction; Aminonitriles; Racemase; Enzyme catalytic promiscuity; Chemistry; Kemi; Organic chemistry; Organisk kemi; Bioorganic chemistry; Bioorganisk kemi;

   Sammanfattning : Combined thermodynamic/kinetic events amount to a kinetically controlled Dynamic Combinatorial Resolution (DCR) process, where the lability of themolecules/aggregates are used to generate dynamics, and the species experiencing the lowest activation energy is selected via kinetic process. Bothinter- and intramolecular processes can be performed using this concept,resulting in complete resolution and associated amplification of the selected species. LÄS MER

5. 9. Dynamic Systems for Screening, Control and Identification of Protein-Ligand Interactions

   Författare :Rikard Larsson; Olof Ramström; Michel R. Gagné; KTH; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Dynamic combinatorial chemistry; Dynamic kinetic combinatorial resolution; Catalytic screening; Transthiolesterification; Thiol disulfide interchange; Nitroaldol reaction; Lectins; Hydrolases; Dynamic self-inhibition; Organic chemistry; Organisk kemi;

   Sammanfattning : Dynamic systems for screening, control and identification of different protein-ligand interactions are presented. Dynamic chemistry is used to produce new compounds/constituents in situ that can interact with a target molecule. Several entities can be introduced at the same time and interact with one another. LÄS MER

7. 10. Pulse oximetry: Evaluation of a potential tool for early detection of critical congenital heart disease

   Författare :Anne de-Wahl Granelli; Göteborgs universitet; []
   Nyckelord :pulse oximetry; duct-dependent; newborn screening; congenital heart disease; perfusion index;

   Sammanfattning : Background: About one third of newborns with life-threatening congenital heart disease leave newborn nurseries without the problem being recognized, and risk death or serious damage from circulatory collapse. The main aim of this thesis has been to evaluate if routine newborn screening with pulse oximetry could improve early in-hospital detection of newborns with duct-dependent circulation (DDC). LÄS MER