Sökning: "Dynamic combinatorial chemistry"

Visar resultat 1 - 5 av 8 avhandlingar innehållade orden Dynamic combinatorial chemistry.

  1. 1. Dynamic Sulfur Chemistry Screening, Evaluation and Catalysis

    Detta är en avhandling från Stockholm : KTH

    Författare :Rémi Caraballo; KTH.; [2010]
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Dynamic combinatorial chemistry; dynamic sulfur chemistry; thioglycoside; mutarotation; disulfide metathesis; hemithioacetal formation; 1H STD-NMR; inhibition; phosphine; Concanavalin A; beta-galactosidase; dynamic drug discovery.; NATURAL SCIENCES Chemistry; NATURVETENSKAP Kemi; NATURAL SCIENCES Chemistry Organic chemistry; NATURVETENSKAP Kemi Organisk kemi; NATURAL SCIENCES Chemistry Organic chemistry Bioorganic chemistry; NATURVETENSKAP Kemi Organisk kemi Bioorganisk kemi;

    Sammanfattning : This thesis deals with the design, formation and evaluation of dynamic systems constructed by means of sulfur-containing reversible reactions, in organic and aqueous media and under mild conditions.In a first part, the synthesis of thioglycoside derivatives, constituting the biologically relevant starting components of the dynamic systems, is described. LÄS MER

  2. 2. Discovery-Oriented Screening of Dynamic Systems: Combinatorial and Synthetic Applications

    Detta är en avhandling från Stockholm : KTH

    Författare :Marcus Angelin; KTH.; [2010]
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; chemical education; crystallization; dynamic combinatorial chemistry; dynamic combinatorial resolution; dynamic system; enzyme catalysis; isoindolinone; lipase; nitroalcohol; nitroaldol reaction; phthalide; reversible; secondary alcohol; systems chemistry; tandem reaction; NATURAL SCIENCES Chemistry Organic chemistry; NATURVETENSKAP Kemi Organisk kemi; NATURAL SCIENCES Chemistry Organic chemistry Bioorganic chemistry; NATURVETENSKAP Kemi Organisk kemi Bioorganisk kemi;

    Sammanfattning : This thesis is divided into six parts, all centered around the development of dynamic (i.e., reversibly interacting) systems of molecules and their applications in dynamic combinatorial chemistry (DCC) and organic synthesis. LÄS MER

  3. 3. Catalysis in Dynamic Systems: Control within Molecular Reaction Networks

    Detta är en avhandling från Stockholm : Kungliga Tekniska högskolan

    Författare :Fredrik Schaufelberger; KTH.; [2017]
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; systems chemistry; dynamic covalent chemistry; catalyst screening; reaction networks; organocatalysis; imine exchange; combinatorial chemistry; dynamic systemic resolution; feedback; error-correction; Morita-Baylis-Hillman reaction; C-H activation; H-bond catalysis; transamination; Kemi; Chemistry;

    Sammanfattning : Life as we know it is based on complex networks of biochemical reactions that constantly interact within large dynamic systems. The field of systems chemistry uses chemical models to study how reaction networks – and thereby life – function on a molecular level. LÄS MER

  4. 4. Dynamic Systems for Screening, Control and Identification of Protein-Ligand Interactions

    Detta är en avhandling från Stockholm : KTH

    Författare :Rikard Larsson; KTH.; [2008]
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Dynamic combinatorial chemistry; Dynamic kinetic combinatorial resolution; Catalytic screening; Transthiolesterification; Thiol disulfide interchange; Nitroaldol reaction; Lectins; Hydrolases; Dynamic self-inhibition; NATURAL SCIENCES Chemistry Organic chemistry; NATURVETENSKAP Kemi Organisk kemi;

    Sammanfattning : Dynamic systems for screening, control and identification of different protein-ligand interactions are presented. Dynamic chemistry is used to produce new compounds/constituents in situ that can interact with a target molecule. Several entities can be introduced at the same time and interact with one another. LÄS MER

  5. 5. Reversible Sulfur Reactions in Pre-Equilibrated and Catalytic Self-Screening Dynamic Combinatorial Chemistry Protocols

    Detta är en avhandling från Stockholm : KTH

    Författare :Rikard Larsson; KTH.; [2006]
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Dynamic Combinatorial Chemistry; Reversible sulfur reactions; Catalytic self-screening; Carbohydrates; Lectins; Quartz Crystal Microbalance; NATURAL SCIENCES Chemistry Organic chemistry; NATURVETENSKAP Kemi Organisk kemi;

    Sammanfattning : Dynamic Combinatorial Chemistry (DCC) is a recently introduced supramolecular approach to generate dynamically interchanging libraries of compounds. These libraries are made of different building blocks that reversibly interact with one another and spontaneously assemble to encompass all possible combinations. LÄS MER