Sökning: "clear cell renal cell carcinoma"

Visar resultat 6 - 10 av 31 avhandlingar innehållade orden clear cell renal cell carcinoma.

  1. 6. DNA methylation as a prognostic marker in clear cell Renal Cell Carcinoma

    Författare :Emma Andersson-Evelönn; Sofie Degerman; Magnus Hultdin; Göran Roos; Börje Ljungberg; Ralph Peeker; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Clear cell renal cell carcinoma; DNA methylation; Prognosis; Clinical outcome; Epigenetic classifiers;

    Sammanfattning : Clear cell renal cell carcinoma (ccRCC) is the most common type of renal cell carcinoma worldwide. Metastatic ccRCC is correlated to poor prognosis whereas non-metastatic disease has a 5-year survival rate up to 90%. LÄS MER

  2. 7. Diet and renal cell carcinoma

    Författare :Bahram Rashidkhani; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Renal cell carcinoma (RCC) represents 80-85% of all tumors of the kidney and is responsible for about 2% of all cancer deaths in developed countries. Its incidence varies among countries, among migrants, and by socioeconomic status suggesting that environmental factors play a major etiological role. LÄS MER

  3. 8. Vascular endothelial growth factor in renal cell carcinoma

    Författare :Jan Jacobsen; Börje Ljungberg; Kjell Grankvist; Torgny Rasmuson; Anders Bergh; Peter Ekman; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; VEGF; isoforms; quantitative RT-PCR; immunohistochemistry; tissue microarray; Western blot; stage; survival; renal cell carcinoma; Urology and andrology; Urologi och andrologi;

    Sammanfattning : Background. Angiogenesis is essential for tumour growth. Vascular endothelial growth factor (VEGF) and its isoforms were investigated in relation to the clinical course in a large number of patients with renal cell carcinoma (RCC). Methods. LÄS MER

  4. 9. Notch Signaling in Neuroblastoma and Renal Cell Carcinoma

    Författare :Jonas Sjölund; Institutionen för translationell medicin; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; differentiation; clear cell renal cell carcinoma; neuroblastoma; TGF-beta; migration; γ-secretase; valproic acid; cancer; Notch; ERK; von Hippel-Lindau; hypoxia;

    Sammanfattning : The Notch signaling pathway governs cell functions essential for normal development and organogenesis. Aberrant Notch signaling has been implicated in tumorigenesis by perturbing control of proliferation, differentiation, apoptosis, migration and angiogenesis. LÄS MER

  5. 10. TGF-B signaling in Neuroblastoma and Renal Cell Carcinoma

    Författare :Anna-Karin Boström; Institutionen för translationell medicin; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Renal Cell Carcinoma; ATN; Regeneration; Notch; TGF-B; EMT; Neuroblastoma; MYCN; miR-17-92;

    Sammanfattning : The tubular cells of the adult kidney are normally mitotically quiescent, in stark contrast to the massive regenerative capacity of the injured renal epithelium. In Paper I we characterized a new cell population of progenitor cells using ALDH as a selection marker. LÄS MER