Sökning: "chronic active hepatitis"

Visar resultat 6 - 8 av 8 avhandlingar innehållade orden chronic active hepatitis.

  1. 6. Design and synthesis of inhibitors that target the serine protease thrombin, the malarial aspartyl proteases plasmepsin I and II, and the hepatitis C virus NS3 serine protease

    Författare :Per-Ola Johansson; Mats Larhed; Linköpings universitet; []
    Nyckelord :NATURAL SCIENCES; NATURVETENSKAP;

    Sammanfattning : This thesis addresses the design, synthesis, and structure-activity relationships of protease inhibitors that target the serine protease thrombin, the malarial aspartic proteases plasmepsin I and II, and the hepatitis C virus (HCV) NS3 serine protease. Furthermore, the backgrounds of each of the three types of diseases in question are discussed in detail, and consideration is given as to why it is assumed that inhibition of the mentioned proteases will help prevent or cure cardiovascular diseases, malaria, and hepatitis C. LÄS MER

  2. 7. Serologic Markers in Screening for Coeliac Disease, Clinical significance and immunogenetic basis

    Författare :Klas Sjöberg; Gastroenterologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Gastro-enterology; transglutaminase; specificity; sensitivity; prevalence; HLA; liver disease; endomysial antibodies; gliadin antibodies; diabetes; Autoimmune disease; coeliac disease; Gastroenterologi;

    Sammanfattning : The prevalence of coeliac disease (CD) was initially estimated to 1/1537. Based on serial analysis [GA and endomysial antibodies (EMA)], the prevalence was 6/1970 (0.30%). In autoimmune chronic hepatitis 5. LÄS MER

  3. 8. Harnessing T cell immunity for the prevention and treatment of liver cancer

    Författare :Panagiota Maravelia; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Hepatocellular carcinoma (HCC) accounts for more than 80% of all diagnosed cases of liver cancer which is a major cause of cancer related fatalities worldwide. With few improvements in the survival rates during the last decades, prevention of HCC is key in reducing its burden globally. LÄS MER