Sökning: "cholinesterase inhibitor"

Hittade 5 avhandlingar innehållade orden cholinesterase inhibitor.

  1. 1. Long-term treatment response, predictors and biochemical markers in Alzheimer’s disease

    Författare :Åsa Wallin; Klinisk minnesforskning; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; treatment response; cholinesterase inhibitor; CSF-biomarkers; pre-treatment progression; predictors; Alzheimer’s disease;

    Sammanfattning : Alzheimer’s disease (AD) is clinically characterised by an insidious onset with progressive symptoms of memory impairment, dysphasia, dyspraxia, dygnosia and visuospatial difficulties. Degeneration of neurons in specific regions of the brain, formation of senile plaques and neurofibrillary changes are some of the neuropathological features of the disease. LÄS MER

  3. 2. Long Term Outcome and Prediction Models of Cognition, Activities of Daily Living and Nursing Home Placement in Alzheimer’s Disease with Cholinesterase Inhibitor Treatment

    Författare :Carina Wattmo; Klinisk minnesforskning; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; longitudinal studies; nursing home placement; activities of daily living; cognition; Alzheimer s disease; cholinesterase inhibitors; disease progression; predictors; statistical models.;

    Sammanfattning : Background Prospective longitudinal studies in Alzheimer's disease (AD) that include cholinesterase inhibitor (ChEI) treatment in routine clinical settings are scarce. The patients vary in severity of the disease, clinical course, rate of progression and response to treatment. LÄS MER

  4. 3. Functional brain activity in Alzheimer patients as studied by multi-tracer positron emission tomography : effects of treatment with cholinesterase inhibitors

    Författare :Ahmadul Kadir; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Alzheimer’s disease; cholinesterase inhibitors; positron emission tomography; nicotinic acetylcholine receptor; acetylcholinesterase; multi-tracer; 11C-nicotine; 11C-PMP; 18F-FDG; 11C-PIB; donepezil; rivastigmine; galantamine; phenserine.;

    Sammanfattning : Alzheimer’s disease (AD) is a progressive neurodegenerative disease accompanied by cognitive impairment and disturbances in several neurotransmitter systems, especially the cholinergic system. Studies have correlated the cognitive impairment observed in AD patients with a deficit in central cholinergic neurotransmission. LÄS MER

  5. 4. On The Innervation of Salivary Glands and Treatment of Dry Mouth - An Experimental and Clinical Study

    Författare :Nina Khosravani; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Parotid gland; Denervation; Acetylcholine synthesis; Otic ganglion; Auriculo-temporal nerve; Facial nerve; Neuropeptides; Salivary gland hypofunction; Physostigmine;

    Sammanfattning : Detailed knowledge of the innervation of the parotid gland is essential in basic studies on various neuroglandular phenomena as well as in various types of orofacial surgery. The innervation is more complex than usually depicted in Textbooks. LÄS MER

  7. 5. Economic evaluation of treatments for Alzheimer's disease

    Författare :Linus Jönsson; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Dementia; costs; quality of life; caregivers;

    Sammanfattning : Alzheimer's disease (AD) is the most common cause of dementia, leading to progressive cognitive impairment and loss of functional abilities for die afflicted patient, a heavy burden on caregivers and high costs for society. New treatment strategies are being introduced setting focus on the need to make informed decisions on the allocation of resources to and within dementia care. LÄS MER