Sökning: "hypervalent iodine compounds"
Visar resultat 1 - 5 av 15 avhandlingar innehållade orden hypervalent iodine compounds.
1. Development and Applications of Hypervalent Iodine Compounds : Powerful Arylation and Oxidation Reagents
Sammanfattning : The first part of this thesis describes the efficient synthesis of several hypervalent iodine(III) compounds. Electron-rich diaryliodonium salts have been synthesized in a one-pot procedure, employing mCPBA as the oxidant. Both symmetric and unsymmetric diaryliodonium tosylates can be isolated in high yields. LÄS MER
2. Selective Transformations of Allylic Compounds and Enol Derivatives : Synthesis of Fluorinated and Nitrogenated Scaffolds
Sammanfattning : In this thesis, new synthetic methods to give access to molecules having fluorinated scaffolds and other polar functional groups have been developed. The methods give access to highly valuable organic compounds that may serve as building blocks in the synthesis of functionalized drug candidates. LÄS MER
3. Bifunctionalization of Small Organic Molecules Based on Fluorine Incorporation
Sammanfattning : The dissertation work that is summarized in this thesis describes novel syntheses of organofluorine compounds with a broad coverage of different fluorine-containing motifs.Chapter 2.1 covers works on the exploration of new trifluoromethylthiolating reactions of diazocarbonyl compounds. LÄS MER
4. Metal-Free O- and C-Arylation with Diaryliodonium Salts
Sammanfattning : This thesis concerns the development of metal-free applications using diaryliodonium salts. The first project describes an arylation protocol of allylic and benzylic alcohols in aqueous media. The method proceeds under mild conditions and the ether products were obtained in moderate to good yields. LÄS MER
5. Novel Applications of Benziodoxole Reagents in the Synthesis of Organofluorine Compounds
Sammanfattning : This thesis concerns method development of new synthetic routes by applying electrophilic hypervalent iodine reagents, such as trifluoromethyl-benziodoxole (Togni reagent) and fluoro-benziodoxole. The first project involved the addition of an oxygen moiety and trifluoromethyl group across double and triple bonds (both groups derived from the hypervalent iodine reagent). LÄS MER