Sökning: "chaperone"

Visar resultat 26 - 30 av 170 avhandlingar innehållade ordet chaperone.

  1. 26. Chaperone/usher machinery : a catalyst of virulence organelle assembly

    Författare :Xiaodi Yu; Sveriges lantbruksuniversitet; Sveriges lantbruksuniversitet; []
    Nyckelord :LANTBRUKSVETENSKAPER; AGRICULTURAL SCIENCES;

    Sammanfattning : Many virulence organelles of Gram-negative bacterial pathogens are assembled via the periplasmic chaperone/usher (CU) pathway. The assembly process is a complex task, involving secretion of organelle subunits via the two membranes and periplasm, subunit folding and assembly. LÄS MER

  3. 27. Functional characterization of the yeast ER packaging chaperone Shr3p

    Författare :Fredrik Gilstring; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : All living cells are enclosed by a plasma membrane (PM). The PM is a dynamic structure comprised of lipids and proteins that establishes and maintains the integrity of the cell. Cells utilize the PM to regulate metabolism by selectively altering the flow of metabolites entering the cell. The integral protein components of the PM, e. LÄS MER

  4. 28. Regulation of dioxin receptor function by the Hsp90 chaperone complex

    Författare :Arunas Kazlauskas; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : In mammals the basic helix-loop-helix/Per-Arnt-Sim (bHLH/PAS) family of transcription factors includes the dioxin receptor which is a ligand-dependent transcription factor which mediates biological effects of environmental pollutants such as 2,3,7,8-tetrachlorodibenzo-rho-dioxin (dioxin). In the absence of ligand, the dioxin receptor is associated with the molecular chaperone Hsp90 and two Hsp90-interacting proteins, the co-chaperone p23 and an immunophilin-like protein XAP2. LÄS MER

  5. 29. Study on the Function of Translation Initiation Factor IF1

    Författare :Victor Croitoru; Leif A. Isaksson; Kim Kusk Mortensen; Stockholms universitet; []
    Nyckelord :translation; initiation factor IF1; mutagenesis; A-site; RNA chaperone; NATURAL SCIENCES; NATURVETENSKAP;

    Sammanfattning : Initiation is the first step in protein biosynthesis representing a fundamental event in cell life which determines fidelity, efficiency and regulation of gene expression. In addition to the ribosome and mRNA, three protein factors IF1, IF2 and IF3 are involved in the initiation of translation in prokaryotes. LÄS MER

  7. 30. Conformational Studies of Biologically Active Peptides

    Författare :Björn Walse; Biofysikalisk kemi; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; PapD chaperone; P pili; desmopressin; DDAVP; protein-peptide interactions; glycopeptides; peptide design; transferred NOE; molecular dynamics simulations; circular dichroism; peptide conformation; NMR spectroscopy; immunogenic glycopeptides; Physical chemistry; Fysikalisk kemi;

    Sammanfattning : In this work conformational studies have been performed on peptides from four different systems in an attempt to gain knowledge about their biological function. Circular dichroism (CD) spectroscopy and nuclear magnetic resonance (NMR) spectroscopy in combination with distance geometry and restrained molecular dynamics simulations were the methods used. LÄS MER