Sökning: "Arunas Kazlauskas"

Hittade 1 avhandling innehållade orden Arunas Kazlauskas.

1. 1. Regulation of dioxin receptor function by the Hsp90 chaperone complex

   Författare :Arunas Kazlauskas; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :;

   Sammanfattning : In mammals the basic helix-loop-helix/Per-Arnt-Sim (bHLH/PAS) family of transcription factors includes the dioxin receptor which is a ligand-dependent transcription factor which mediates biological effects of environmental pollutants such as 2,3,7,8-tetrachlorodibenzo-rho-dioxin (dioxin). In the absence of ligand, the dioxin receptor is associated with the molecular chaperone Hsp90 and two Hsp90-interacting proteins, the co-chaperone p23 and an immunophilin-like protein XAP2. LÄS MER