Sökning: "bone marrow stem cells"

Visar resultat 16 - 20 av 176 avhandlingar innehållade orden bone marrow stem cells.

  1. 16. Immune modulation by mesenchymal stem cells

    Författare :Ida Rasmusson; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Mesenchymal stem cells; T cells; cytotoxic T lymphocytes; cytokines; mixed lymphocyte culture; B cells; antibody production; stem cell transplantation; acute graft versus host disease;

    Sammanfattning : Mesenchymal stem cells (MSCs) were discovered as adherent cells in the bone marrow stroma that could form bone and stimulate hematopoiesis. Later, MSCs were shown to be hypoimmunogenic and to suppress proliferation of activated T cells. LÄS MER

  3. 17. The Role of Kit and Thrombopoietin in Regulation of Hematopoietic Stem Cells

    Författare :Lina Thorén; Stamcellscentrum (SCC); []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; thrombopoietin; hematopoiesis; Thpo; c-kit; stem cells;

    Sammanfattning : The hematopoietic stem cell (HSC) is postulated to be the ultimate hematopoietic precursor providing production of mature blood cells, and is characterized by a life long capacity for self-renewal and multilineage differentiation. In a healthy human, the HSC produces 1,000,000,000,000 cells per day, illustrating the high turnover within the hematopoietic system and the need for replenishments by HSCs. LÄS MER

  4. 18. Human Bone Marrow Mesenchymal Stromal Stem Cells in Health and Disease

    Författare :Dimitra Zacharaki; Avdelningen för molekylär hematologi; []
    Nyckelord :;

    Sammanfattning : .... LÄS MER

  5. 19. Allogeneic stem cell transplantation : patients’ and sibling donors’ perspectives

    Författare :Annika M Kisch; Malmö högskola; []
    Nyckelord :Allogeneic haematopoietic stem cell transplantation; Confidentiality; Information and care model; Quality of life; Perspectives; Sibling donor; Stem cell donation;

    Sammanfattning : Allogeneic haematopoietic stem cell transplantation (hereafter HSCT) is an established treatment which offers a potential cure for a variety of diseases, mainly haematological malignancies. However, the treatment is also associated with significant risks of acute complications and late side effects, including mortality. LÄS MER

  7. 20. Defining Regulators of Human Hematopoietic Stem Cells

    Författare :Christine Karlsson; Avdelningen för molekylärmedicin och genterapi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; High-throughput screening; Expansion; Hematopoietic stem cell; Cord blood; RNA interference; extrinsic Signaling molecules;

    Sammanfattning : Bone marrow transplantation (BMT) is a conceptual and elegant example of stem cell therapy, rendered possible by the dual capacity of hematopoietic stem cells (HSCs) to self-renew and differentiate. These defining features ultimately ensure the production of all blood cell lineages and simultaneous maintenance of the stem cell pool, thereby maintaining lifelong homeostasis. LÄS MER