Sökning: "bone marrow progenitor cells"

Visar resultat 16 - 20 av 97 avhandlingar innehållade orden bone marrow progenitor cells.

1. 16. Mast Cell Progenitor Trafficking in Allergic Airway Inflammation

   Författare :Joakim Dahlin; Jenny Hallgren; Hans-Reimer Rodewald; Uppsala universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Mast cells; mast cell progenitors; allergy; asthma; allergic airway inflammation; IgE; lung; CD11c;

   Sammanfattning : Mast cell progenitors originate from the bone marrow and migrate to the lungs via the blood. During maturation, these cells acquire granules that contain a potent array of bronchoconstrictive mediators. LÄS MER

3. 17. Live and Let Die : Critical regulation of survival in normal and malignant hematopoietic stem and progenitor cells

   Författare :Pernilla Eliasson; Jan-Ingvar Jönsson; Mikael Sigvardsson; Urban Gullberg; Linköpings universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; hematopoietic stem cells; hypoxia; self-renewal; survival; acute myeloid leukemia; FLT3; Cell and molecular biology; Cell- och molekylärbiologi; Haematology; Hematologi;

   Sammanfattning : The hematopoietic stem cell (HSC) is characterized by its ability to self-renew and produce all mature blood cells throughout the life of an organism. This is tightly regulated to maintain a balance between survival, proliferation, and differentiation. LÄS MER

4. 18. Mechanisms of allergic airway inflammation. Role of bone marrow

   Författare :Svetlana Sergejeva; Göteborgs universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; asthma; eosinophil; CD34 cell; eosinophilopoiesis; IL-17;

   Sammanfattning : Allergic airway (AW) inflammation is characterized by accumulation of inflammatory cells within the AW. It is likely that the accumulation of cells within AW is a combination of increased production, migration and prolonged survival of the cells. Inflammatory cells develop from CD34+hematopoietic progenitor cells. LÄS MER

5. 19. Stem and progenitor cell involvement in acute lymphoblastic leukemia

   Författare :Anders Castor; Stamcellscentrum (SCC); []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; cancer; Haematology; Cytology; oncology; cancerology; Cytologi; onkologi; Medicin människa och djur ; Medicine human and vertebrates ; ETV6-RUNX1; BCR-ABL1; stem cells; Acute lymphoblastic leukemia; extracellular fluids; Hematologi; extracellulära vätskor;

   Sammanfattning : Leukemic stem cells (LSCs) share the capacity of self renewal and extensive proliferation with normal hematopoietic stem cells (HSCs), and are therefore obvious targets for therapy. As such, they need to be identified and characterized in order to elucidate what drives them, and what separates them from their normal counterparts. LÄS MER

7. 20. Targeting residual malignant cells in myeloid leukemia

   Författare :Malin Nilsson; Göteborgs universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; acute myeloid leukemia; chronic myeloid leukemia; histamine dihydrochloride; hydroxyurea; leukemic stem cells;

   Sammanfattning : Malignant cells persisting during treatment prevent cure in many patients with myeloid leukemia. In acute myeloid leukemia (AML), the failure to eradicate the leukemic clone during conventional chemotherapy is associated with leukemic relapse, mostly with dismal survival outcome. LÄS MER