Sökning: "biological chemistry"

Visar resultat 26 - 30 av 851 avhandlingar innehållade orden biological chemistry.

  1. 26. Interaction of trehalose with water and protein for the understanding of biological stabilization

    Författare :Christoffer Olsson; Chalmers tekniska högskola; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; trehalose; protein; neutron scattering; water; neutron diffraction; amorphous; cryopreservation; biomolecule; EPSR; DSC;

    Sammanfattning : The understanding of biomolecular interactions with water and co-solutes opens up further understanding for the mechanism behind biomolecular stabilization. This is highly important for developing technologies aimed to preserve biological material. Such techniques include cryopreservation of for example pharmaceuticals or human organ transplants. LÄS MER

  3. 27. Physical characterization of exosomes and other extracellular vesicles using surface-based sensing

    Författare :Deborah Rupert; Chalmers tekniska högskola; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; nanoparticle tracking analysis; exosomes; scattering; surface-based biosensing; optical density; cluster of differentiation 63 CD63 ; liposomes; label-free; fluorescence; surface plasmon resonance; Extracellular vesicles; specificity; antibody; lipid content; single particle; quantification; size distribution; optical waveguide microscopy;

    Sammanfattning : Extracellular vesicles (EVs) are hundred of nanometer sized particles secreted by almost all cell types. Exosomes are one type of EVs today intensively investigated due to the increased evidence suggesting that they play important roles as communicating vehicles in a broad range of physiological processes, pathological conditions and disease diagnostics. LÄS MER

  4. 28. Polyelectrolyte Brush Electrodes for Protein Capture and Release

    Författare :Gustav Ferrand-Drake Del Castillo; Chalmers tekniska högskola; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; pH-responsive interfaces; Polyelectrolyte brushes; protein immobilization; electrochemistry.;

    Sammanfattning : Stimuli-responsive polyelectrolyte brushes switch as a function of pH between a charged and neutral state that affects their electrostatic interactions with other charged molecules like proteins. Adjustment of the pH results in the binding of large quantities of proteins making polyelectrolyte brushes widely used as biointerfaces. LÄS MER

  5. 29. Unraveling the importance of thiol compounds on mercury speciation, uptake and transformation by the iron-reducer Geobacter sulfurreducens

    Författare :Mareike Franziska Gutensohn; Erik Björn; Ulf Skyllberg; Jeffra K. Schaefer; Vera Slaveykova; Umeå universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; mercury; low molecular mass thiols; speciation; uptake; methylation; reduction; Hg 0 ; Hg II ; MeHg; Geobacter sulfurreducens; ICP-MS; LC-MS MS; X-ray absorption spectroscopy; cell physiology;

    Sammanfattning : The biogenic methylation of inorganic, divalent mercury (Hg(II)) by methylating microorganisms leads to formation and bioaccumulation of monomethyl mercury (MeHg) in the environment and can cause severe damage to ecosystems and human health. Diverse microorganisms carry the gene sequence hgcAB and are able to methylate Hg(II) intracellularly. LÄS MER

  7. 30. Spectroscopic studies of biomolecules confined in self-assembled nanostructures

    Författare :Nils Carlsson; Chalmers tekniska högskola; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY;

    Sammanfattning : The present thesis examines the effects of incorporating biomolecules into self-assembled nanostructures. This approach is exemplified by short DNA molecules in environments close to lipid bilayers and the immobilization of enzymes into mesoporous silica particles. LÄS MER