Sökning: "beta-catenin"

Visar resultat 1 - 5 av 27 avhandlingar innehållade ordet beta-catenin.

  1. 1. LTD4 signalling via beta-catenin: a possible link between inflammation and cancer

    Författare :Maryna Mezhybovska; Malmö Cellpatologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; LTD4; beta-catenin; colorectal cancer; CysLT1R; proliferation; inflammation;

    Sammanfattning : The pro-inflammatory mediator LTD4 is an important component in the pathogenesis of inflammatory conditions as inflammatory bowel diseases. Patients suffering from inflammatory bowel diseases face an increased risk of intestinal cancer development. LÄS MER

  2. 2. Wnt/beta-catenin signaling in midbrain dopaminergic neurons

    Författare :Nina Rawal; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; Dopamine; neuron; development; beta-catenin; Writ; Parkin; Parkinson s disease;

    Sammanfattning : Parkinson's disease (PD) is caused by a progressive degeneration of the dopaminergic (DA) neurons of the substantia nigra. However, the mechanisms underlying the degeneration remain elusive and there is no cure for P1) at present. LÄS MER

  3. 3. Cell adhesion proteins in different invasive patterns of colon carcinomas : a morphometric and molecular genetic study

    Författare :Victoria Hahn-Strömberg; Lennart Franzén; Richard Palmqvist; Örebro universitet; []
    Nyckelord :AGRICULTURAL SCIENCES; LANTBRUKSVETENSKAPER; LANTBRUKSVETENSKAPER; AGRICULTURAL SCIENCES; colon carcinoma; growth pattern; tight junction; Complexity Index; cell adhesion; E-cadherin; Beta-catenin; Occludin; Claudin.; Medicine; Medicin; Biomedicin; Biomedicine;

    Sammanfattning : Colorectal carcinoma is the second most common type of cancer in both men and women in Sweden. Cancer of the colon and rectum are often considered together and their ten year survival rate is approximately 50 – 60 % depending on sex and location. LÄS MER

  4. 4. A cohort study of sex differences and prognostic biomarkers in colorectal cancer

    Författare :Sakarias Wangefjord; Tumörmikromiljö; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; colorectal cancer; prognosis; treatment prediction; biomarkers; sex differences; cyclin D1; microsatellite instability; beta-catenin; KRAS mutation; BRAF mutation; EGFR expression; EGFR gene copy number alterations;

    Sammanfattning : Colorectal cancer (CRC) is one of the most common forms of cancer worldwide, with an annual incidence of more than 1 million cases. Despite advancements in the management of CRC, mortality remains high. LÄS MER

  5. 5. Associations of sex, anthropometric and reproductive factors with clinicopathological and molecular characteristics of colorectal cancer

    Författare :Jenny Brändstedt; Tumörmikromiljö; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; colorectal cancer; carcinogenesis; MDCS; anthropometrics; risk factors; sex differences; hormonal therapy; beta-catenin; cyclin D1; p53; MSI; KRAS mutation; BRAF mutation;

    Sammanfattning : Colorectal cancer (CRC) is the third most common cancer globally, with approximately 1.2 million new cases every year. The highest incidence rates are seen in developed countries, thereby imposing dietary and lifestyle factors in the etiology of CRC. LÄS MER