Sökning: "basement membrane"

Visar resultat 21 - 25 av 86 avhandlingar innehållade orden basement membrane.

1. 21. Quiescent cancer cells : Three-dimensional cell models for evaluation of new therapeutics

   Författare :Frida Ek; Mårten Fryknäs; Malin Jarvius; Rolf Larsson; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Cancer; cancer cell quiescence; dormancy; three-dimensional; multicellular tumor spheroids; model development; cancer pharmacology; mitochondria; OXPHOS; colorectal carcinoma; hepatocellular carcinoma; Medicinsk vetenskap; Medical Science;

   Sammanfattning : Inadequate metabolic conditions in solid tumors lead to the formation of quiescent cancer cells that are suspended in a transient cell cycle arrest. When conditions change, quiescent cancer cells can re-enter the cell cycle and cause recurrence. LÄS MER

3. 22. Angiogenic growth factors : mechanism of action and function in vascular development

   Författare :Charlotte Rolny; Andrius Kazlauskas; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Molecular medicine; PDGF-BB; VEGF; angiogenesis; hypoxia; migration; heparin; Molekylärmedicin; Molecular medicine genetics and pathology ; Molekylär medicin genetik och patologi ; Molecular Medicine; molekylär medicin genetik och patologi ;

   Sammanfattning : The mature vascular system is composed of a network of blood vessels organized into arteries, capillaries, and veins. The vessels are composed of endothelial cells surrounded by smooth muscle cells and embedded in a specialized basement membrane. LÄS MER

4. 23. Functional and molecular aspects of the glomerular barrier

   Författare :Anna Björnson Granqvist; Göteborgs universitet; []
   Nyckelord :glomerular endothelium; glycocalyx; podocyte; proteoglycan; glycosaminoglycans; nephrotic syndrome;

   Sammanfattning : The kidneys are crucial for maintaining a normal salt-water balance in the body, which is a prerequisite for life. They do that by filtering 180 liters of plasma per day across the highly permselective glomerular barrier and reabsorbing 99 % of the filtrate. LÄS MER

5. 24. Studies on the interaction of human cells with transplantable materials for skin repair and cardiovascular surgery

   Författare :Katarina Jansson; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :Cell culture; Keratinocytes; Fibroblasts; Endothelial cells; Reepithelialization; In vitro endothelialization; Tissue engineering; Biomaterial: Dermal substitute; Synthetic vascular graft; Heart valve bioprosthesis;

   Sammanfattning : Tissue engineering is becoming an important field for the development of new tissues in vitro for replacement of diseased or worn out parts of the body. This thesis describes some characteristics of cultured human cells seeded on transplantable materials for skin repair and cardiovascular surgery. LÄS MER

7. 25. Flexible fiberoptic bronchoscopy : studies on methods for the diagnosis of carcinoma of the lung, bronchial mucosal damage and haemodynamic effects

   Författare :Rune Lundgren; Umeå universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Flexible fiberoptic bronchoscopy; bronchial carcinoma; brush biopsy; respiratory mucosal damage; regeneration; mucociliary clearance; haemodynamic effects; hypoxemia;

   Sammanfattning : The diagnostic accuracy attained with the use of transbronchial fine needle aspiration biopsy, aspiration of bronchial secretion, bronchial washing, brush biopsy and forceps biopsy via a flexible fiberoptic bronchoscope was compared in patients with carcinoma of the lung. In endoscopic visible tumours the sensitivity of forceps biopsy was higher than that of the other methods. LÄS MER