Sökning: "basement membrane"

Visar resultat 11 - 15 av 86 avhandlingar innehållade orden basement membrane.

  1. 11. Vascular remodelling and circulating basement membrane fragments in abdominal aortic aneurysm

    Författare :Mari Holsti; Malin Sund; Anders Wanhainen; Joakim Nordanstig; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; AAA; extracellular matrix; vascular remodelling; collagen; inflammation; Surgery; kirurgi;

    Sammanfattning : An abdominal aortic aneurysm (AAA) is a degenerative disease, characterized by advanced inflammation and extracellular matrix (ECM) remodelling. Enhanced protease activity mediated by cytokines results in the degradation of ECM proteins, leading to the generation of different bioactive fragments. LÄS MER

  3. 12. Surgical outcomes of phototherapeutic keratectomy on Epithelial basement membrane dystrophy, and the characterisation of Bowman´s Layer

    Författare :Johan Germundsson; Neil Lagali; Per Fagerholm; Jesper Hjortdal; Linköpings universitet; []
    Nyckelord :;

    Sammanfattning : Background. Epithelial basement membrane dystrophy (EBMD) is a common disease of the anterior cornea that can lead to problems with vision and/or painful recurrent erosions of the corneal epithelium. Several treatment options have been used, but recurrence of EBMD after treatment is a problem. LÄS MER

  4. 13. Laminins and alpha11 integrin in the human eye : importance in development and disease

    Författare :Berit Byström; Fatima Pedrosa Domellöf; Ulf Stenevi; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; basement membranes; extracellular matrix; laminin; integrin; cornea; development; keratoconus; wound healing; remodeling; immunohistochemistry; Ophtalmiatrics; Oftalmiatrik;

    Sammanfattning : The extracellular matrix (ECM) offers a protective shelter for cells and provides signaling paths important for cell to cell communication. ECM consists of basement membranes (BM) and interstitial matrix. BMs provide mechanical support for parenchymal cells, influence cell proliferation, survival, migration and differentiation. LÄS MER

  5. 14. Expression, recognition and usage of laminin-8 (a4b1g1, Lm-411) by monocytes and neutrophils

    Författare :Zenebech Wondimu; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Basement membrane; laminins; myeloid cells; extravasation; migration.;

    Sammanfattning : Laminins (LNs) are a family of large alphabetagamma heterotrimeric glycoproteins found in all basement membranes (BMs). They are expressed in a tissue- and developmental stagespecific manner and implicated in vital cellular functions, including cell adhesion, migration and signaling. LÄS MER

  7. 15. Bacterial interaction with the fibrinolytic system and extracellular matrix

    Författare :Thomas Herrman Eberhard; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :plasminogen; extracellular matrix; basement membrane; virulence factors; fibronectin; vitronectin; collagen; Haemophilus influenzae Neisseria meningitidis Streptococcus pneumoniae;

    Sammanfattning : Bacterial infection of host organisms is a state of complex interaction between the parasite and the host. Two critical steps in the infectious process are: Adhesion to the epithelial surfaces and penetration of tissue barriers to gain entrance to tissues and into the circulation. These two steps have been the subjects of this thesis. LÄS MER