Sökning: "vascular remodelling"

Visar resultat 1 - 5 av 32 avhandlingar innehållade orden vascular remodelling.

  1. 1. Vascular remodelling and circulating basement membrane fragments in abdominal aortic aneurysm

    Detta är en avhandling från Umeå : Umeå Universitet

    Författare :Mari Holsti; Umeå universitet.; [2019]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; AAA; extracellular matrix; vascular remodelling; collagen; inflammation; Surgery; kirurgi;

    Sammanfattning : An abdominal aortic aneurysm (AAA) is a degenerative disease, characterized by advanced inflammation and extracellular matrix (ECM) remodelling. Enhanced protease activity mediated by cytokines results in the degradation of ECM proteins, leading to the generation of different bioactive fragments. LÄS MER

  2. 2. Aspects on Imaging and Endovascular Treatment of Aortic Dissection and Aneurysm

    Detta är en avhandling från Uppsala : Acta Universitatis Upsaliensis

    Författare :Mats-Ola Eriksson; Uppsala universitet.; [2013]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Aneurysms; aorta; stents; ultrasound; colour Doppler; vascular; interventional; aortic dissection; complicated; TEVAR; EVAR; re-intervention; survival; thrombosis; false lumen; aortic remodelling; Radiology; Radiologi;

    Sammanfattning : Aortic aneurysm and dissections are potentially life threatening conditions. The advent of endovascular aortic repair (EVAR) and thoracic endovascular aortic repair (TEVAR) has reduced perioperative mortality and morbidity and are now established therapy methods for treatment of aortic disease. LÄS MER

  3. 3. Integration of signalling in smooth muscle caveolae

    Detta är en avhandling från Department of Experimental Medical Science, Lund Univeristy

    Författare :Yulia Shakirova; [2010]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Caveola; caveolin; detrusor; cavin; smooth muscle contractility; remodelling; NO; vascular dysfunction; smooth muscle; erectile dysfunction;

    Sammanfattning : Caveolae and lipid rafts are plasma membrane microdomains that are considered to play a role in cellular signalling. Caveolins and cavins as well as cholesterol are required for the structure and function of caveolae. The papers summarized in this thesis examine the role of caveolae in smooth muscle function. LÄS MER

  4. 4. Pulmonary hypertension. Clinical and pathophysiological studies

    Detta är en avhandling från Department of Experimental Medical Science, Lund Univeristy

    Författare :Nedim Selimovic; Göteborgs universitet.; Gothenburg University.; [2008]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Pulmonary hypertension; Echocardiography; Right heart catheterisation; Pulmonary vascular resistance; Pulmonary function tests; Lung transplantation; Mortality on the waiting list; Vascular remodelling; Growth substances; Inflammation; Endothelin;

    Sammanfattning : Pulmonary hypertension (PH) is a common abnormality, most often associated with various cardiopulmonary diseases. Pulmonary arterial hypertension (PAH) is a devastating pulmonary vascular disease characterised by the proliferation of endothelial, smooth-muscle cells and fibroblasts. LÄS MER

  5. 5. Functions of Pericytes in Ischemic Stroke

    Detta är en avhandling från Lund University: Faculty of Medicine

    Författare :Michaela Roth; [2019]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Stroke; Pericytes; RGS5; Blood-brain barrier; vascular remodelling; scar formation;

    Sammanfattning : Ischemic stroke remains one of the leading causes of death and disability worldwide, and its burden is predicted to further increase due to the aging population. The only available treatments, thrombolysis or thrombectomy, can only be applied within a limited time window after stroke onset, and thus are applicable only to a small proportion of stroke patients. LÄS MER