Sökning: "autoantigens"

Visar resultat 16 - 20 av 51 avhandlingar innehållade ordet autoantigens.

1. 16. The importance of psychological and physical stressors on diabetes-related immunity in a young population – an interdisciplinary approach

   Författare :Emma Carlsson; Maria Faresjö; Arne Gerdner; Anneli Frostell; Kristina Lejon; Jönköping University; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; psychological stressors; physical stressors; cellular immune system; type 1 diabetes; young population;

   Sammanfattning : Background: The prevalence of immunological disorders such as type 1 diabetes (T1D) is increasingly common amongst children, adolescents and young adults. There is also an increase in psychosomatic symptoms (depression, insomnia, anxiety, headaches and fatigue etc. LÄS MER

3. 17. Clinical and experimental studies of organ-specific autoimmune diseases : With special reference to Addison's disease and autoimmune hepatitis : by Gennet Gebre-Medhin

   Författare :Gennet Gebre-Medhin; Uppsala universitet; []
   Nyckelord :Medical sciences; Addison s Disease; replacement therapy; DHEA; autoimmune hepatitis; APS I; autoantigen; cytochrome P4501A2; aromatic L-amino acid decarboxylase; MEDICIN OCH VÅRD; MEDICINE; MEDICIN; Medicine; medicin;

   Sammanfattning : Organ-specific autoimmunity constitutes a large health problem, where both the clinical management and our understanding of the pathogenetic mechanisms need to improve. Women with Addison's disease have abnormally low levels of dehydroepiandrosterone (DHEA), its sulphate ester (DHEA-S) and androgens relative to age, and many patients complain of physical and mental fatigue and low stress tolerance. LÄS MER

4. 18. Aspects of ZnT8 autoimmunity in childhood type 1 diabetes

   Författare :Cecilia K Andersson; Pediatrisk endokrinologi; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Type 1 diabetes; Zinc transporter; ZnT8 autoantibodies; HLA; islet cell autoantibodies; GAD65 autoantibodies; IA-2 autoantibodies; insulin autoantibodies; glucose tolerance;

   Sammanfattning : Type 1 diabetes is one of the most common chronic diseases in childhood and adolescence with an increasing incidence worldwide. It is an autoimmune disease with many autoimmune markers, where the zinc transporter 8 autoantibody (ZnT8A) is the most recent autoantibody discovered. LÄS MER

5. 19. Alopecia and vitiligo in autoimmune polyendocrine syndrome type I

   Författare :Håkan Hedstrand; Uppsala universitet; []
   Nyckelord :Medical sciences; APS I; autoantigen; vitiligo; alopecia areata; cDNA-library; immunoscreening; tyrosine hydroxylase; SOX9; SOX10; molecular mimicry; MEDICIN OCH VÅRD; MEDICINE; MEDICIN; Medicine; medicin;

   Sammanfattning : Autoimmune polyendocrine syndrome type I (APS I) is a recessively inherited disease caused by mutations in a recently identified gene, AIRE, on human chromosome 21. APS I patients are affected by autoimmune destruction of multiple endocrine glands and other organs as well as ectodermal structures. LÄS MER

7. 20. Studies on autoimmune diabetes in Latvians and other populations

   Författare :Aija Shtauvere-Braméus; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :;

   Sammanfattning : IDDM is an autoimmune disease, characterized by autoimmune mediated loss of insulin secreting B- cells. GAD65 and IA-2 are major B-cell specific autoantibodies and are not found in healthy population. IDDM is associated with certain HLA class II alleles. IDDM is positively associated with HLA DR3 and DR4 in Caucasians. LÄS MER