Sökning: "replacement therapy"

Visar resultat 1 - 5 av 242 avhandlingar innehållade orden replacement therapy.

  1. 1. Hormone replacement therapy : benefits and adverse effects

    Författare :Inga-Stina Ödmark; Mats Hammar; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; hormone replacement therapy HRT ; bleeding pattern; progestogen; wellbeing; side effects; lipoprotein a ; Obstetrics and gynaecology; Obstetrik och gynekologi; obstetrik och gynekologi; Obstetrics and Gynaecology;

    Sammanfattning : Background: Numerous studies have shown that estrogen replacement therapy (ERT) is an effective treatment for vasomotor symptoms, insomnia and vaginal dryness. Beneficial effects have also been shown on lipid patterns and on the incidence of osteoporotic fractures. LÄS MER

  3. 2. Hormone replacement therapy in rheumatoid arthritis

    Författare :Helena Forsblad d'Elia; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Rheumatoid arthritis; randomised controlled trials; hormone replacement therapy; estrogen; osteoporosis; bone mineral density; bone remodelling; cartilage remodelling; cytokines; insulin-like growth factor 1;

    Sammanfattning : Rheumatoid arthritis (RA) is 2-3 times more frequent in women as compared to men. The peak incidence in women coincides with the years around the menopause and the course of RA is also influenced by events associated with hormonal alterations. LÄS MER

  4. 3. Hormone replacement therapy and effects on mood

    Författare :Inger Björn; Inger Sundström-Poromaa; Torbjörn Bäckström; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; adverse effects; estradiol; hormone replacement therapy HRT ; mood; negative side effects; progestins;

    Sammanfattning : Background: During the past 5 decades, hormone replacement therapy (HRT) has been used, and appreciated for its beneficial effects, by millions of women in their menopause. As treatment for climacteric symptoms, estrogen is outstanding, and effects on hot flushes, vaginal dryness, and insomnia have been widely documented. LÄS MER

  5. 4. Cell Replacement Therapy for Parkinson's Disease: Potential for Circuitry Repair

    Författare :Tiago Cardoso; Utvecklings- och regenerativ neurobiologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Rabies-based tracing; Parkinson s disease cell therapy; Cell Replacement Therapy; Human embryonic stem cells; Dopamine neuron; Synaptic integration; circuitry repair;

    Sammanfattning : The derivation of dopamine neurons from human embryonic stem cells (hESCs) now offers a promising alternative to fetal tissue for cell replacement therapy (CRT) in Parkinson´s disease (PD). Using the appropriate chemical cues in vitro, hESCs can be patterned towards bona-fide ventral midbrain (VM) DA neurons that survive, reinnervate, release DA and provide functional recovery when transplanted into rodent and non-human primate models of PD. LÄS MER

  7. 5. Exploring Patient-Specific Cell Replacement Therapy for Parkinson's Disease

    Författare :Shelby Shrigley; Utvecklings- och regenerativ neurobiologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; dopaminergic neurons; Parkinson s disease; cell replacement therapy; cellular reprogramming; alpha-synuclein;

    Sammanfattning : Parkinson’s disease (PD) affects over six million people worldwide and is characterised by the progressive loss of dopaminergic (DA) neurons in the substantia nigra, accumulation of pathological alpha-synuclein (αSyn), and inflammation in the brain. This leads to motor impairments including rigidity, akinesia, bradykinesia, resting tremor, and postural instability. LÄS MER