Sökning: "molecular mimicry"
Visar resultat 1 - 5 av 10 avhandlingar innehållade orden molecular mimicry.
Sammanfattning : Translation is a central biological process, that is catalysed by a machinery consisting of RNA and protein. In this thesis three different protein components of the bacterial protein synthesis system have been structurally studied. LÄS MER
Sammanfattning : Autoimmune polyendocrine syndrome type I (APS I) is a recessively inherited disease caused by mutations in a recently identified gene, AIRE, on human chromosome 21. APS I patients are affected by autoimmune destruction of multiple endocrine glands and other organs as well as ectodermal structures. LÄS MER
3. Cell-penetrating peptides in protein mimicry and oligonucleotide delivery : Applications and mechanisms
Sammanfattning : The plasma membrane functions as a barrier, restricting entry of hydrophilic pharmaceutical agents. Cell-penetrating peptides (CPPs) are capable of transporting bioactive cargos into the cell and have consequently been extensively investigated for their mechanism of entry and capability to deliver various cargos spanning from peptides to plasmids. LÄS MER
Sammanfattning : Biological and chemical reactions involved in physiological processes are often complex and very sophisticated. Such processes can be mimicked in the laboratory to obtain important knowledge, valuable for the development of new diagnostic methods, drugs and biosensors. LÄS MER
5. Murine B lymphocyte growth regulation : a study of host defence factors and their mimicry by Mycoplasma arginini
Sammanfattning : Immune responses are the result of extended clonal growth and maturation of specific precursors preexisting in low frequencies. Clonal expansion is partly controlled by soluble factors, thus, their identification is essential for the understanding of the immune response regulation. LÄS MER