Sökning: "autoantigens"
Visar resultat 6 - 10 av 51 avhandlingar innehållade ordet autoantigens.
6. Immune responses to the Ro and La autoantigens
Sammanfattning : Sjögren's syndrome (SS) and systemic lupus erythematosus (SLE) are rheumatic diseases characterized by autoantibody production directed to the Ro/SS-A and La/SS-B autoantigens. The Ro/SS-A is a complex of one of four small RNAs denoted hY RNAs, and three proteins; Ro 60kD, Ro 52kD and La. LÄS MER
7. Autoantigens in Inflammatory Bowel Disease and Primary Sclerosing Cholangitis
Sammanfattning : Inflammatory bowel disease (IBD) comprises diseases that are characterized by chronic or relapsing inflammation of the gastrointestinal tract. Primary sclerosing cholangitis (PSC) is an extraintestinal manifestation in IBD. LÄS MER
8. Humoral immunity to recombinant human autoantigens in organ-specific autoimmune disease
Sammanfattning : Insulin-dependent diabetes mellitus (IDDM) and idiopathic Addison's disease are organ-specific autoimmune diseases characterized by the presence of circulating autoantibodies. The role of autoantibodies in the pathogenesis of these diseases is not fully understood, but their presence can be used as a marker for diagnosis and prediction. LÄS MER
9. Pteridine dependent hydroxylases as autoantigens in autoimmune polyendocrine syndrome type 1
Sammanfattning : Autoimmune polyendocrine syndrome type I (APS) is a monogenous, recessively inherited disease characterised by endocrine and non-endocrine autoimmune manifestations. One fifth of APS I patients suffer from periodic intestinal dysfunction with varying degrees of malabsorbtion, steatorrhea and constipation. LÄS MER
10. Studies on the role of autoantibodies and autoantigens in rheumatoid arthritis and myositis
Sammanfattning : A major population of patients affected with rheumatoid arthritis (RA) and inflammatory idiopathic myopathies (IIM, collectively called myositis) is characterized by the presence of autoantibodies. The pathogenic impact of anti-citrullinated protein/peptide (ACPA) or anti-histidyl transfer RNA synthetase (HisRS; Jo1) autoantibodies remains largely unknown. LÄS MER