Sökning: "association mapping"
Visar resultat 1 - 5 av 130 avhandlingar innehållade orden association mapping.
1. Genetic Mapping of Susceptibility Genes for Systemic Lupus Erythematosus
Sammanfattning : Systemic lupus erythematosus (SLE) is a complex autoimmune disease with unknown etiology. The aim of this thesis was to identify susceptibility regions through genetic mapping, using model-based linkage analysis on nuclear and extended SLE multicase families. LÄS MER
2. Functional association networks for disease gene prediction
Sammanfattning : Mapping of the human genome has been instrumental in understanding diseasescaused by changes in single genes. However, disease mechanisms involvingmultiple genes have proven to be much more elusive. Their complexityemerges from interactions of intracellular molecules and makes them immuneto the traditional reductionist approach. LÄS MER
3. Single Base Station mmWave Radio Positioning, Mapping, and SLAM
Sammanfattning : Fifth-generation (5G) communication systems in Frequency Range 2, operating above 24 GHz and utilizing mmWave signals, showcase distinct properties that open up new possibilities in positioning, mapping, and simultaneous localization and mapping (SLAM). The combination of large bandwidth, extensive antenna arrays, and high carrier frequency results in geometric-based signals, and unprecedented delay and angle resolution. LÄS MER
4. Dissecting the Genetic Basis of Systemic Lupus Erythematosus : The Pursuit of Functional Variants
Sammanfattning : Systemic lupus erythematosus (SLE) is a chronic and systemic autoimmune disease that primarily affects women during the childbearing years. SLE is characterized by the production of autoantibodies against nucleic acids and their interacting proteins. LÄS MER
5. Genomic strategies towards the dissection of human complex disease
Sammanfattning : Complex diseases are caused by the activities of many genes acting in concert with environmental factors. A major challenge facing human genetic research is to unravel the genetic factors behind complex disorders. LÄS MER