Sökning: "microgel"

Visar resultat 1 - 5 av 17 avhandlingar innehållade ordet microgel.

  1. 1. Microgel Interactions with Peptides and Proteins Consequence of Peptide and Microgel Properties

    Detta är en avhandling från Uppsala : Acta Universitatis Upsaliensis

    Författare :Ronja Widenbring; Martin Malmsten; Per Hansson; Catherine Picart; [2015]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Binding; Degradation; Enzyme; Gel; Hydrogel; Microgel; Peptide; Protein; Release; Pharmaceutical Physical Chemistry; Farmaceutisk fysikalisk kemi;

    Sammanfattning : Microgels are lightly cross-linked hydrogel particles in the sub-micrometer to micrometer size range with a capacity to drastically change their volume in response to changes in the external environment. Microgels have an ability to bind and store substances such as biomacromolecular drugs, notably proteins and peptides, and release them upon stimuli, making them potential candidates as drug delivery vehicles and functional biomaterials. LÄS MER

  2. 2. Fluids, Gels and Crystals : Phase behavior of binary thermoresponsive microgel mixtures

    Detta är en avhandling från Kemiska institutionen, Lunds universitet

    Författare :Jasper Immink; [2019-03]
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; colloidal phase behavior; microgel; binary mixture; colloidal gel; sequential gelation; patchy particle; binary crystal; crystal-to-crystal transition;

    Sammanfattning : Thermoresponsive colloidal microgels expel solvent from their interior upon crossing a threshold temperature, resulting in a significantly reduced size. The collapse of microgels can reversibly switch the interparticle interactions from soft repulsive to attractive, and the accompanying size reduction allows for precise control over volume fraction. LÄS MER

  3. 3. Interaction Between Microgels and Oppositely Charged Proteins

    Detta är en avhandling från Uppsala : Acta Universitatis Upsaliensis

    Författare :Christian Johansson; Per Hansson; Brian Saunders; [2009]
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; microgel; protein; uptake; distribution; core-shell; colloidal stability; NATURAL SCIENCES Chemistry Physical chemistry; NATURVETENSKAP Kemi Fysikalisk kemi; Physical Chemistry; fysikalisk kemi;

    Sammanfattning : This thesis reports on interactions between microgels and oppositely charged proteins. Two types of negatively charged microgels are investigated: poly(acrylic acid) microgels of 60-80 µm in diameter, and colloidal poly(NIPAM-co-acrylic acid) microgels of around 1 µm in diameter. LÄS MER

  4. 4. In vitro evaluation of formulations used in the treatment of hepatocellular carcinoma

    Detta är en avhandling från Uppsala : Acta Universitatis Upsaliensis

    Författare :Emelie Ahnfelt; Hans Lennernäs; Erik Sjögren; Niklas Axén; Jesper Østergaard; [2018]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Drug delivery system; Doxorubicin; Microgel; Emulsion; Hepatocellular carcinoma; Biofarmaci; Biopharmaceutics;

    Sammanfattning : Hepatocellular carcinoma (HCC) causes ~ 600,000 deaths annually, making it the second most deadly cancer form. HCC is classified into five stages and for the intermediate HCC treatment, the two most commonly used drug delivery systems (DDSs) are lipiodol-based emulsions and drug-eluting beads. LÄS MER

  5. 5. Phase Phenomena in Polymer Networks Empirical Studies on the Influence of Hydrophobicity, Charge Density and Crosslinks on Macroion-Induced Phase Transitions in Polyelectrolyte Gels

    Detta är en avhandling från Uppsala : Acta Universitatis Upsaliensis

    Författare :Martin Andersson; Per Hansson; Lennart Piculell; [2011]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Gel; microgel; microsphere; polystyrenesulfonate; polyacrylate; polyacrylicacid; DoTAB; DoTAC; CTAB; CTAC; network; polyelectrolyte; complex salt; self assembly; phase behaviour; hysteresis; thermodynamic; core-shell; lysozyme; cytochrome c; microscopy; micromanipulator; elastomer; elastic; protein; surfactant; phase behaviour; sorting; PHARMACY; FARMACI; NATURAL SCIENCES Chemistry Physical chemistry; NATURVETENSKAP Kemi Fysikalisk kemi;

    Sammanfattning : The thesis concerns polyelectrolyte gels in contact with oppositely charged proteins and surfactant micelles, and includes of four papers (I-IV). In paper I confocal Raman spectroscopy was introduced as a method to trace micelles and investigate the structure of gel-surfactant complexes, in phase separated gel spheres. LÄS MER