Sökning: "carbohydrate-based particles"

Hittade 4 avhandlingar innehållade orden carbohydrate-based particles.

  1. 1. Novel allergen preparations for use in allergen-specific immunotherapy

    Författare :Theresa Neimert Andersson; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Allergy; allergen-specific immunotherapy; adjuvants; carbohydrate-based particles; allergic asthma; mouse models; hypoallergens;

    Sammanfattning : Allergy is a common disease in the industrialized countries, affecting approximately 25% of the population. Therefore, there is a need to find new treatment strategies to improve the quality of life for allergic individuals. Today the only treatment that gives long-lasting reduction of allergic symptoms is allergen-specific immunotherapy (SIT). LÄS MER

  2. 2. Novel treatment strategies and regulation of IgE-mediated allergic disease

    Författare :Sarah Thunberg; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Allergic symptoms such as rhinoconjunctivitis, asthma or gastrointestinal symptoms, triggered by inhaled or ingested allergens cross-linking allergen-specific IgE on mast cells or basophils, are defined as IgE-mediated allergy. The major allergens from birch pollen (Bet v 1) and cat dander (Fel d 1) are two common allergens eliciting allergic disease. LÄS MER

  3. 3. Development of a Sel-tag for multimodality imaging and studies of mammalian thioredoxin reductase 1

    Författare :Qing Cheng; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Selenocysteine (Sec; U in one-letter code), the 21st amino acid existing in all selenoproteins, has unique biochemical properties due to its selenium atom, including a low pKa and a high reactivity with many electrophilic agents. When a selenoprotein is translated, the insertion of Sec occurs at a UGA codon, normally yielding translational termination. LÄS MER

  4. 4. Diagnosis of IgE-mediated allergy : new approaches using recombinant allergens

    Författare :Hans Grönlund; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Allergens; allergy; cat; diagnostics; immunotherapy; recombinant allergens;

    Sammanfattning : More than 10% of the population in industrialized countries suffer from lgE-mediated cat allergy. Allergens produced by recombinant techniques offer new possibilites to diagnose and treat allergic patients but will also help to uncover the mechanisms behind the sensitisation. LÄS MER