Sökning: "experimental allergen challenge"

Visar resultat 1 - 5 av 14 avhandlingar innehållade orden experimental allergen challenge.

  1. 1. Effect of allergen specific immunotherapy on allergic inflammation in the upper and lower airways

    Författare :Monica Arvidsson; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; birch pollen allergy; cat allergy; specific immunotherapy; rush immunotherapy; experimental allergen challenge; late asthmatic response;

    Sammanfattning : Experimental allergen challenge is widely used in diagnostic practice and research in allergy, but its relationship to environmental exposures is not clarified. Both models of allergic diseases have been used in order to examine the effects of allergen specific immunotherapy (SIT). LÄS MER

  3. 2. Eosinophil Inflammation in Allergic Disease : Clinical and experimental studies in allergic asthma and allergic rhinitis

    Författare :Mary Kämpe; Marie Carlson; Christer Janson; Gunnemar Stålenheim; Magnus Sköld; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Allergic asthma; allergic rhinitis; eosinophils; pollen season; bronchial challenge; nasal challenge eosinophil degranulation; PI3K signalling; Allergology; Allergologi; Lung Medicine; Lungmedicin; Lung Medicine; Lungmedicin;

    Sammanfattning : Allergic diseases are chronic inflammatory conditions, characterised by eosinophil inflammation systemically and in target organs, where cytotoxic granule proteins are responsible for tissue injury. Allergic rhinitis is known to be a risk factor for the development of asthma, yet not all with rhinitis develop asthma. LÄS MER

  4. 3. Clinical and experimental studies in nickel allergy

    Författare :Monica Hindsén; Dermatologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; nickel absorption; Nickel; allergic contact dermatitis; patch test reactivity; flare-up reactions; oral nickel provocation; previous contact dermatitis; hand eczema; atopy; Dermatology; venereology; Dermatologi; venereologi;

    Sammanfattning : Kliniska och experimentella studier av nickelallergi Nickelallergi är vanligt, särskilt hos kvinnor. Nickelallergi leder ofta till periodiskt eller kroniskt eksem, främst på händerna. Dessa eksem kan vara svårläkta och leda till långa sjukskrivningsperioder. LÄS MER

  5. 4. Immunoregulation in an experimental model of allergic asthma

    Författare :Magnus Korsgren; Avdelningen för klinisk kemi och farmakologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; allergic asthma; macrophage migration inhibitory factor; eosinophils; gd T cells; NK1.1 T cells; natural killer cells; immunoglobulins; B cells; innate immunity; allergic airway inflammation; immediate hypersensitivity; Physiology; Fysiologi; Immunology; serology; transplantation; Immunologi; serologi;

    Sammanfattning : In allergic asthma the immune response to antigen is inappropriate, leading to an inflammatory process in the respiratory mucosa. To further elucidate immunological mechanisms involved in the development of such inflammation, control mice and mice deficient in selected cell types or proteins, were used in experimental models of allergic asthma and anaphylaxis. LÄS MER

  7. 5. Immunological and inflammatory mechanisms in ocular allergy with special reference to vernal keratoconjunctivitis : clinical and experimental studies

    Författare :Per Montan; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :allergic conjunctivitis; allergen challenge; atopy; conjunctival biopsy; eosinophils; ECP; IgE; immunohistochemistry; inflammation; interleukins; T-cells; tears; vernal keratoconjunctivitis;

    Sammanfattning : Ocular allergy encompasses a wide range of conditions, most of which implicate IgE in the pathogenesis. In contrast to the benign nature of seasonal allergic conjunctivitis (SAC), the less common chronic eye diseases vernal and atopic keratoconjunctivitis (VKC and AKC) are severe and debilitating disorders. LÄS MER