Sökning: "anticoagulant"

Visar resultat 36 - 40 av 103 avhandlingar innehållade ordet anticoagulant.

  1. 36. Haemostatic changes in plasma for transfusion during preparation and storage

    Författare :Anna-Maija Suontaka; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :transfusion plasma; cold activation; contact system; coagulation; fibrinolysis; citrates; methylene blue; fibrinogen; stability;

    Sammanfattning : The haemostatic quality of plasma for transfusion is liable to be affected by techniques for preparation and storage. We have studied changes in the contact system, coagulation and fibrinolysis under the following conditions: blood drawn into a half-strength citrate anticoagulant solution, virus inactivation of plasma with methylene blue and red light, and plasma storage in the fluid phase. LÄS MER

  2. 37. Coagulation in children with liver disease

    Författare :Maria Magnusson; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :FVIIa;

    Sammanfattning : About 100 new children in Sweden require care at a tertiary pediatric ward each year for severe liver disease. These children are at risk for both severe gastrointestinal bleeding, which may be life threatening, and intra- or extrahepatic thrombosis. LÄS MER

  3. 38. Structural and Functional Studies of Gas6

    Författare :Jonas Stenhoff; Malmö Klinisk kemi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Klinisk kemi; Clinical chemistry; EDTA; calcium; multimer; monomer; platelets; Mer; Axl; vitamin K; Gas6; human circulation; soluble receptor; Tyro3; receptor tyrosine kinases; growth factor;

    Sammanfattning : The vitamin K-dependent and ubiquitously expressed 82 kDa glycoprotein product of the growth-arrest-specific-gene 6, Gas6, shows 44% sequence identity to the anticoagulant protein, protein S. Both proteins share further the same domain organization. LÄS MER

  4. 39. Structural and functional studies of C4b-binding protein (C4BP)

    Författare :Lena Kask; Malmö Klinisk kemi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; phagocytosis; apoptosis; protein S; complement control protein CCP domains; factor H fH ; Complement; C4b-binding protein C4BP ; intracellular assembly; Clinical chemistry; Klinisk kemi;

    Sammanfattning : The subject of this thesis is complement inhibitor C4b-binding protein (C4BP), on which we have performed both structural and functional studies. Complement is part of the innate immune defence and eliminates microbes, solubilises immune complexes and is involved in the clearance of apoptotic cells. LÄS MER

  5. 40. Venous thromboembolism in women : risk factors and long term follow-up

    Författare :Kristina Sonnevi; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Background: Venous thromboembolism (VTE) is a common and potentially life threatening disease. Women have different risk factors than men at both first and recurrent VTE. The aim of this thesis was to further identify and explore risk factors for VTE in young and middle aged women. LÄS MER