Sökning: "Axl"

Visar resultat 1 - 5 av 10 avhandlingar innehållade ordet Axl.

  1. 1. Structural and Functional Studies of Gas6

    Författare :Jonas Stenhoff; Malmö Klinisk kemi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Klinisk kemi; Clinical chemistry; EDTA; calcium; multimer; monomer; platelets; Mer; Axl; vitamin K; Gas6; human circulation; soluble receptor; Tyro3; receptor tyrosine kinases; growth factor;

    Sammanfattning : The vitamin K-dependent and ubiquitously expressed 82 kDa glycoprotein product of the growth-arrest-specific-gene 6, Gas6, shows 44% sequence identity to the anticoagulant protein, protein S. Both proteins share further the same domain organization. LÄS MER

  3. 2. Axl RTK and microRNAs in urogenital cancers

    Författare :Helena Fritz; Malmö Klinisk kemi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Sammanfattning : This thesis is based on four projects focused on the Axl receptor tyrosine kinase (RTK) and microRNAs in clear cell renal cell carcinoma (ccRCC) and in prostate cancer (PCa). Paper I focuses on differentially expressed microRNAs in ccRCC. LÄS MER

  4. 3. The Soluble Form of the Axl Receptor Tyrosine Kinase

    Författare :Carl Ekman; Malmö Klinisk kemi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Sammanfattning : The present investigation focus on the receptor Axl, which is a member of the receptor tyrosine kinase family. Axl is activated by the ligand Gas6 inducing cell growth and proliferation, but also regulate inflammation and vascular homeostasis. LÄS MER

  5. 4. A multifaceted study of the receptor tyrosine kinase Axl with focus on Renal Cell Carcinoma

    Författare :Anna Gustafsson; Malmö Klinisk kemi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Sammanfattning : The present investigation is a multifaceted study of the receptor tyrosine kinase Axl, whose overexpression and activation is implicated in several human malignancies, with focus on renal cell carcinoma (RCC). At first, our main interest concerned the intracellular Axl interactor named Tensin2 (Tns2) and its family member Tensin3 (Tns3). LÄS MER

  7. 5. Occupying Time : Design, Time, and the Form of Interaction

    Författare :Ramia Mazé; RISE; []
    Nyckelord :SAMHÄLLSVETENSKAP; SOCIAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Design; Architecture;

    Sammanfattning : As technology pervades our everyday life and material culture, new possibilities and problematics are raised for design. Attention in contemporary design discourse is shifting ‘beyond the object’, to the qualities of processes and experiences. LÄS MER