Sökning: "anti-rheumatic drugs"
Visar resultat 1 - 5 av 19 avhandlingar innehållade orden anti-rheumatic drugs.
1. Persistent inflammatory pathways in rheumatoid arthritis despite anti-rheumatic treatment
Sammanfattning : The past years have witnessed tremendous progress in the treatment of rheumatoid arthritis, a chronic debilitating autoimmune disease mainly characterized by joint inflammation with progressive tissue destruction and loss of function. This condition affects 0. LÄS MER
2. Studies of the Role of the Gastrointestinal Tract in Children with Juvenile Idiopathic Arthritis (JIA)
Sammanfattning : Juvenile idiopathic arthritis (JIA) is the most common rheumatic disease in children, but its cause is not fully established. Changes in the intestinal canal and an unfavourable composition of gut bacteria have been suggested as factors that can increase the risk of developing JIA and influence the disease course. LÄS MER
3. Associations Between Rheumatoid Arthritis and Malignant Lymphomas
Sammanfattning : Patients with rheumatoid arthritis (RA) are at increased risk of developing malignant lymphoma, although details about this association remain unclear. The aims of this thesis were to investigate risk factors for lymphoma in patients with RA and to characterize these lymphomas regarding subtype, presence of Epstein-Barr virus (EBV), clinical manifestations and prognosis. LÄS MER
4. Studies on the therapeutic modulation of inflammation in the synovial membrane of rheumatoid arthritis
Sammanfattning : Rheumatoid arthritis (RA) is a chronic autoimmune disease characterized by inflammation of the synovial membrane that can lead to joint deformity and physical disability. Despite recent progress in the therapeutic field of RA, the exact molecular mechanisms responsible for chronic joint inflammation are not yet completely understood. LÄS MER
5. Patient Reported Outcomes and Orthopedic Surgery in Rheumatoid Arthritis
Sammanfattning : Orthopedic surgery is used effectively in many patients with severe rheumatoid arthritis RA). The aim of modern pharmacologic treatment is to prevent joint destruction and reduce the need for orthopedic surgery. Patient reported outcomes (PROs) are important measures of the burden of RA. LÄS MER