Sökning: "Kjell Alving"

Visar resultat 1 - 5 av 6 avhandlingar innehållade orden Kjell Alving.

  1. 1. Towards Improved Diagnostics and Monitoring in Childhood Asthma : Methodological and Clinical Aspects of Exhaled NO and Forced Oscillation Technique

    Författare :Charlotte Heijkenskjöld Rentzhog; Malinovschi Andrei; Lennart Nordvall; Kjell Alving; Lauri Lehtimäki; Uppsala universitet; []
    Nyckelord :MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; asthma; children; exhaled NO; forced oscillation technique; airway inflammation; small airways; asthma diagnostics; Pediatrik; Pediatrics; Lungmedicin; Lung Medicine;

    Sammanfattning : Background: Asthma is a heterogeneous disease. Diagnosis relies on symptom evaluation and lung function tests using spirometry. Symptoms can be vague. Spirometry is effort-dependent and does not reliably evaluate small airways. LÄS MER

  2. 2. Development of allergic and respiratory symptoms in adolescence and early adulthood : Risk factors and gender differences

    Författare :Pia Kalm-Stephens; Kjell Alving; Andrei Malinovschi; Åsa Neuman; Gunn Engvall; Eva Rönmark; Uppsala universitet; []
    Nyckelord :MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Adolescents; allergy; asthma; breath test; epidemiology; gender; health status indicator; incidence; nitric oxide; prevalence; wheeze.; Epidemiologi; Epidemiology; Lungmedicin; Lung Medicine; Pediatrik; Pediatrics;

    Sammanfattning : Background: Asthma and allergic diseases have increased in prevalence for several decades and affect a substantial number of individuals in everyday life, as well as their families and public healthcare resources. Subjects with asthma report impaired self-rated health. LÄS MER

  3. 3. Nitric oxide within the concept of united airway disease : Exhaled and nasal nitric oxide in cystic fibrosis, asthma and upper airway inflammatory diseases

    Författare :Christina Krantz; Andrei Malinovschi; Kjell Alving; Celeste Porsbjerg; Uppsala universitet; []
    Nyckelord :MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; nitric oxide; nasal NO; exhaled NO; asthma; cystic fibrosis; airway inflammation; upper airway inflammatory disorders; united airway disease; IgE sensitisation; Lungmedicin; Lung Medicine; Pediatrik; Pediatrics;

    Sammanfattning : Background: Within the concept of united airway disease, it is postulated that inflammatory disorders in the upper and lower airways are interrelated and influence each other. Fractional exhaled nitric oxide (FeNO) is an established biomarker of type-2 inflammation in the lower airways and is elevated in patients with asthma. LÄS MER

  4. 4. Nitric Oxide Exchange in Central and Peripheral Airways : Determinants in Health and Respiratory Disease

    Författare :Andrei Malinovschi; Christer Janson; Kjell Alving; Lena Holm; Elisabeth Bel; Uppsala universitet; []
    Nyckelord :exhaled nitric oxide; alveolar NO; bronchial NO flux; extended NO analysis; asthma; smoking; snus; IgE-sensitization; pharyngo-oral tract; nitrate; nitrite; pulmonary hypertension;

    Sammanfattning : Background: Exhaled nitric oxide (NO) is a marker of eosinophilic steroid-sensitive inflammation in the airways of patients with respiratory disease. Moreover, information about the localization of inflammation in the respiratory tree is obtained by estimates of bronchial and alveolar contributions to exhaled NO. LÄS MER

  5. 5. Study of biomarkers for improved diagnosis and therapy monitoring in young asthmatics

    Författare :Nikolaos Tsolakis; Kjell Alving; Lennart Nilsson; Uppsala universitet; []
    Nyckelord :MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Asthma phenotypes; IgE sensitization; atopy; cat allergen components; exhaled NO; airway hyper-responsiveness; lung function; asthma-related quality of life.;

    Sammanfattning : Background: Type-2 asthma is often related to atopy and is characterized by elevated type-2 biomarkers. However, less is known about the pathophysiology of non-type 2 asthma, factors associated therewith, and the stability of different asthma phenotypes over time. LÄS MER