Sökning: "angiogenesis"

Visar resultat 26 - 30 av 400 avhandlingar innehållade ordet angiogenesis.

  1. 26. Tumor angiogenesis. Regulation of mural cell recruitment and endothelial sprouting

    Författare :Alexandra Abramsson; Göteborgs universitet; []
    Nyckelord :Angiogenesis; tumor; retina; PDGF; VEGF; platelet-derived growth factor; guidance; vascular endothelial growth factor.;

    Sammanfattning : The formation of new blood vessels is an inherent part of many physiological and pathological processes. Currently, there is a strong hope pathological situations like stroke, diabetic retinopathy and cancer may be affected by pharmacological regulators of blood vessel formation. LÄS MER

  3. 27. The Roles of Growth Factor Interactions and Mechanical Tension in Angiogenesis

    Författare :Ludvig Petersson; Pär Gerwins; Filip Farnebo; Uppsala universitet; []
    Nyckelord :angiogenesis; myofibroblast; wound healing; VEGF; FGF; PDGF; endocan; endothelial cell; vascularization; MEDICINE; MEDICIN; Medicin; Medicine;

    Sammanfattning : Angiogenesis, the formation of new blood vessels from preexisting ones through creation of new vessel branch points by sprouting or vessel splitting, is an important part of tissue growth in both physiological processes like wound healing and pathological conditions such as cancer. Growth factors like VEGF-A, FGF-2 and PDGF-BB are involved in both types of angiogenesis. LÄS MER

  4. 28. MOLECULAR ASPECTS OF ENDOTHELIAL CELL FUNCTION AND HYPOXIA-DEPENDENT TUMOR ANGIOGENESIS

    Författare :Paulina Kucharzewska; Bröstcancer-genetik; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; hypoxia; hypoxia-inducible factor; angiogenesis; anti-angiogenic therapy; endothelial cell; polyamines; microRNA; extracellular membrane vesicles; exosomes; glioblastoma;

    Sammanfattning : Hypoxia, or deficient oxygen levels, is an inherent feature of rapidly expanding tumor tissue. In order to survive in the hostile, hypoxic environment and to restore the supply of oxygen and nutrients tumor cells activate a variety of adaptive mechanisms. Among them, hypoxia-induced angiogenesis, i.e. LÄS MER

  5. 29. Molecular Mechanisms of Action of Histidine-rich Glycoprotein in Angiogenesis Inhibition

    Författare :Chunsik Lee; Lena Claesson-Welsh; Jan Palmblad; Uppsala universitet; []
    Nyckelord :Cell and molecular biology; anti-angiogenesis; angiogenesis inhibitor; endothelial cell; histidine-rich glycoprotein; focal adhesion; tumor-associated macrophages; VEGF; MMP; Cell- och molekylärbiologi;

    Sammanfattning : Angiogenesis, de novo synthesis of blood vessels from the pre-existing vasculature, is required both during embryonic development and in pathophysiological conditions. In particular, tumor growth needs new capillary vessels in order to both deliver oxygen and nutrients and to remove toxin and metabolites. LÄS MER

  7. 30. The functional role of neural cell adhesion molecule in pathological angiogenesis

    Författare :Joakim Håkansson; Göteborgs universitet; []
    Nyckelord :N-CAM; pericytes; tumour; PDGF-B; ECM; retina; angiogenesis;

    Sammanfattning : .... LÄS MER