Sökning: "anti-angiogenesis"
Visar resultat 1 - 5 av 7 avhandlingar innehållade ordet anti-angiogenesis.
1. Regulation of Angiogenesis
Sammanfattning : Angiogenesis is the formation of new blood vessels from pre-existing ones. New blood vessel formation is fundamental in processes such as reproduction, embryonic development and wound healing. Growth of neoplasms is accompanied by increased angiogenesis. This thesis describes cellular and molecular mechanisms of importance for angiogenesis. LÄS MER
2. Molecular Mechanisms of Action of Histidine-rich Glycoprotein in Angiogenesis Inhibition
Sammanfattning : Angiogenesis, de novo synthesis of blood vessels from the pre-existing vasculature, is required both during embryonic development and in pathophysiological conditions. In particular, tumor growth needs new capillary vessels in order to both deliver oxygen and nutrients and to remove toxin and metabolites. LÄS MER
3. Experimental therapies of malignant glioma : with emphasis on angiogenesis inhibition
Sammanfattning : Malignant glioma consists of a group of diseases where the localisation and the nature of the disease makes treatment an extreme challenge. Two important biological features of malignant glioma cells are their infiltrative growth and their ability to induce angiogenesis. LÄS MER
4. Aspects on lipoprotein lipase and atherosclerosis
Sammanfattning : Lipoprotein lipase (LPL) hydrolyses blood lipids at the vascular endothelium. This action makes fatty acids available for tissue metabolic requirements. LPL is anchored to the endothelium by electrostatic forces and may act as a bridge connecting lipoproteins to cell surfaces. LÄS MER
5. Angiogenesis regulation in hormone dependent breast- and ovarian cancer
Sammanfattning : Angiogenesis is a key event in tumor progression and a rate-limiting step in the establishment of a clinical cancer disease. The net balance of pro- and anti-angiogenesis mediators in the tissue dictates the angiogenic phenotype of a tumor. LÄS MER
