Sökning: "anti-angiogenesis"

Visar resultat 1 - 5 av 6 avhandlingar innehållade ordet anti-angiogenesis.

  1. 1. Regulation of Angiogenesis

    Detta är en avhandling från Uppsala : Acta Universitatis Upsaliensis

    Författare :Helena Larsson; [2001]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Genetics; angiogenesis; anti-angiogenesis; endostatin; latent antithrombin; prelatent antithrombin; Crk; Genetik; MEDICINE Dermatology and venerology; clinical genetics; internal medicine Clinical genetics; MEDICIN Dermatologi och venerologi; klinisk genetik; invärtesmedicin Klinisk genetik; Pathology; patologi;

    Sammanfattning : Angiogenesis is the formation of new blood vessels from pre-existing ones. New blood vessel formation is fundamental in processes such as reproduction, embryonic development and wound healing. Growth of neoplasms is accompanied by increased angiogenesis. This thesis describes cellular and molecular mechanisms of importance for angiogenesis. LÄS MER

  2. 2. Molecular Mechanisms of Action of Histidine-rich Glycoprotein in Angiogenesis Inhibition

    Detta är en avhandling från Uppsala : Acta Universitatis Upsaliensis

    Författare :Chunsik Lee; Uppsala universitet.; [2006]
    Nyckelord :Cell and molecular biology; anti-angiogenesis; angiogenesis inhibitor; endothelial cell; histidine-rich glycoprotein; focal adhesion; tumor-associated macrophages; VEGF; MMP; Cell- och molekylärbiologi;

    Sammanfattning : Angiogenesis, de novo synthesis of blood vessels from the pre-existing vasculature, is required both during embryonic development and in pathophysiological conditions. In particular, tumor growth needs new capillary vessels in order to both deliver oxygen and nutrients and to remove toxin and metabolites. LÄS MER

  3. 3. Experimental therapies of malignant glioma with emphasis on angiogenesis inhibition

    Detta är en avhandling från Umeå : Umeå universitet

    Författare :Maria Sandström; Roger Henriksson; Mikael Johansson; Anja Smits; [2008]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; glioma; angiogenesis; VEGF; tyrosinekinaseinhibitor; ZD6474; plasminogenactivator; tPA; uPA; proteomics; MEDICINE Surgery Oncology; MEDICIN Kirurgi Onkologi;

    Sammanfattning : Malignant glioma consists of a group of diseases where the localisation and the nature of the disease makes treatment an extreme challenge. Two important biological features of malignant glioma cells are their infiltrative growth and their ability to induce angiogenesis. LÄS MER

  4. 4. Aspects on lipoprotein lipase and atherosclerosis

    Detta är en avhandling från Umeå : Umeå universitet

    Författare :Lucyna Neuger; Philip Barter; [2005]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICINE Physiology and pharmacology Physiology Clinical physiology; MEDICIN Fysiologi och farmakologi Fysiologi Klinisk fysiologi;

    Sammanfattning : Lipoprotein lipase (LPL) hydrolyses blood lipids at the vascular endothelium. This action makes fatty acids available for tissue metabolic requirements. LPL is anchored to the endothelium by electrostatic forces and may act as a bridge connecting lipoproteins to cell surfaces. LÄS MER

  5. 5. Angiogenesis regulation in hormone dependent breast- and ovarian cancer

    Detta är en avhandling från Linköping : Linköping University Electronic Press

    Författare :Christina Bendrik; Charlotta Dabrosin; Malin Sund; [2011]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICINE; MEDICIN;

    Sammanfattning : Angiogenesis is a key event in tumor progression and a rate-limiting step in the establishment of a clinical cancer disease. The net balance of pro- and anti-angiogenesis mediators in the tissue dictates the angiogenic phenotype of a tumor. LÄS MER