Sökning: "FGF"

Visar resultat 1 - 5 av 95 avhandlingar innehållade ordet FGF.

  1. 1. Heparan Sulfate Regulation of Fibroblast Growth Factor (FGF) Receptor-1 Signal Transduction

    Detta är en avhandling från Uppsala : Acta Universitatis Upsaliensis

    Författare :Lars Lundin; Lena Claesson-Welsh; Marco Presta; [2003]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Pathology; FGF; FGFR; dimerisation; signal transduction; heparan sulfate; proteoglycan; heparin; VEGF; embryonal stem cell; endothelial cell; differentiation; Patologi; MEDICINE Morphology; cell biology; pathology Pathology; MEDICIN Morfologi; cellbiologi; patologi Patologi;

    Sammanfattning : Fibroblast growth factors (FGFs) constitute a family (currently FGF-1 to FGF-23) of polypeptides that are essential in embryonal development and adult physiology, in animals from nematodes to humans. FGFs bind to four receptor tyrosine kinases, denoted FGFR-1 to FGFR-4. LÄS MER

  2. 2. The Role of Shb in Angiogenesis, FGF and VEGF Signalling in Endothelial Cells

    Detta är en avhandling från Uppsala : Acta Universitatis Upsaliensis

    Författare :Kristina Holmqvist; Uppsala universitet.; [2004]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Medicine; Shb; Src; FAK; Angiogenesis; VEGFR-2; FGFR-1; Endothelial cells; Spreading; Stress fiber formation; siRNA; VEGF; FGF; Differentiation; Migration; Tube formation; RNAi; Medicin; MEDICINE Dermatology and venerology; clinical genetics; internal medicine; MEDICIN Dermatologi och venerologi; klinisk genetik; invärtesmedicin;

    Sammanfattning : Angiogenesis is defined as the formation of new capillary blood vessels from pre-existing ones. This process involves several steps including: migration, proliferation and differentiation of endothelial cells into blood vessels. LÄS MER

  3. 3. Regulation of morphogen signalling during neural patterning in the Xenopus embryo

    Detta är en avhandling från Department of Laboratory Medicine, Lund University

    Författare :Hooi Min Tan Grahn; [2011]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Suppressor-of-fused; Gli; β-Catenin; Neural; Xenopus; FGF; Signalling; HtrA1; RDH10; Retinol dehydrogenase; Retinoic acid; Spemann s organizer; Induction; Gradient;

    Sammanfattning : Morphogens such as Hedghog, Wnt, FGF, and retinoic acid are important signals whose concentrations need to be tightly regulated in the vertebrate embryo to ensure body axis development and formation of the central nervous system. We first show that the intracellular cytoplasmic protein XSufu acts as a dual regulator of Hedgehog (Hh) and Wnt signals during neural induction and patterning in the Xenopus embryo. LÄS MER

  4. 4. Early Rostrocaudal Patterning of the CNS

    Detta är en avhandling från Umeå : Molekylärbiologi (Teknisk-naturvetenskaplig fakultet)

    Författare :Ulrika Nordström; Thomas Edlund; [2005]
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; CNS development; neural patterning; neural specification; Wnt; FGF; RA; Isthmic organizer; motor neurons; rostrocaudal patterning.; NATURAL SCIENCES Biology Organism biology Developmental biology; NATURVETENSKAP Biologi Organismbiologi Utvecklingsbiologi;

    Sammanfattning : The transformation of an initially uniform population of epiblast cells into an intricately complex central nervous system (CNS) is one of the most fascinating processes during embryonic development. Presumptive neural cells are initially specified as cells of forebrain character. LÄS MER

  5. 5. The Roles of Growth Factor Interactions and Mechanical Tension in Angiogenesis

    Detta är en avhandling från Uppsala : Acta Universitatis Upsaliensis

    Författare :Ludvig Petersson; Pär Gerwins; Filip Farnebo; [2010]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; angiogenesis; myofibroblast; wound healing; VEGF; FGF; PDGF; endocan; endothelial cell; vascularization; MEDICINE; MEDICIN; Medicin; Medicine;

    Sammanfattning : Angiogenesis, the formation of new blood vessels from preexisting ones through creation of new vessel branch points by sprouting or vessel splitting, is an important part of tissue growth in both physiological processes like wound healing and pathological conditions such as cancer. Growth factors like VEGF-A, FGF-2 and PDGF-BB are involved in both types of angiogenesis. LÄS MER