Sökning: "fluorination"
Visar resultat 1 - 5 av 19 avhandlingar innehållade ordet fluorination.
1. Development of new Fluorination Methods Directed to Fluorine-18 Labelling
Sammanfattning : This thesis deals with the development of new fluorination reactions and their application to fluorine-18 labelling. Fluorine-18 labelled compounds are employed as tracers in Positron Emission Tomography (PET), which is a powerful non-invasive imaging method in medical diagnostics. LÄS MER
2. Synthesis of Organofluorine Compounds and Allenylboronic Acids - Applications Including Fluorine-18 Labelling
Sammanfattning : This work is focused on two areas: the chemistry of organofluorine and organoboron compounds. In the first chapter, a copper-catalysed synthesis of tri- and tetrasubstituted allenylboronic acids is presented. Extension of the same method leads to allenylboronic esters. LÄS MER
3. Transition metal-catalyzed allylic and vinylic functionalization : Method development and mechanistic investigations
Sammanfattning : The use of small molecule building blocks in, for example, pharmaceutical research and new material development, creates a need for new and improved organic synthesis methods. The use of transition metals as mediators and catalysts opens up new reaction pathways that have made the synthesis of completely new compounds possible as well as greatly improved the synthetic routes to known compounds. LÄS MER
4. Energy Transfer Processes and Quenching Pathways in Lanthanide Complexes: The Role of Structural Changes
Sammanfattning : Due to their unique magnetic and luminescent properties, trivalent lanthanides (Ln(III)) have been widely utilised in cellular imaging. Ln(III) luminescence is usually sensitized by a light-harvesting ‘antenna’, a chromophore that can transfer the excitation energy to the Ln(III). LÄS MER
5. Bifunctionalization of Small Organic Molecules Based on Fluorine Incorporation
Sammanfattning : The dissertation work that is summarized in this thesis describes novel syntheses of organofluorine compounds with a broad coverage of different fluorine-containing motifs.Chapter 2.1 covers works on the exploration of new trifluoromethylthiolating reactions of diazocarbonyl compounds. LÄS MER
