Sökning: "Zn II"

Visar resultat 21 - 25 av 72 avhandlingar innehållade orden Zn II.

  1. 21. Risk factors and amyotrophic lateral sclerosis : an epidemiologic approach

    Författare :Tracy Peters; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Amyotrophic Lateral Sclerosis (ALS) is a debilitating and rare disorder; progressively the patient’s muscles go into paralyses limiting their ability to walk, do day-to-day tasks, and eat. This thesis covers risk factors related to ALS. LÄS MER

  3. 22. Self-assembly of amyloid-β peptides in the presence of metal ions and interacting molecules – a detour of amyloid building blocks

    Författare :Cecilia Mörman; Astrid Gräslund; Daniel Otzen; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; biophysics; Alzheimer’s disease; protein aggregation; amyloid formation; amyloid-β peptide; aggregation kinetics; interactions; metal ions; designed peptide constructs; Tau protein; NMR; circular dichroism; fluorescence spectroscopy; Biophysics; biofysik;

    Sammanfattning : Misfolding of proteins into amyloid structures is implicated as a pathological feature in several neurodegenerative diseases and the molecular causes are still unclear. One typical characteristic of Alzheimer’s disease is self-assembly and accumulation of soluble amyloid-β (Aβ) peptides into insoluble fibrils and plaques. LÄS MER

  4. 23. Hazard Identification of Anti-fouling Paints and Contaminated Sediments by the Use of Biological Tests in Brackish Water

    Författare :Jenny Karlsson; Britta Eklund; Magnus Breitholtz; Göran Dave; Stockholms universitet; []
    Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Anti-fouling paints; Toxicity tests; Hazard identification; Sediment toxicity; Ceramium tenuicorne; Nitocra spinipes; Environmental engineering; Miljöteknik; Applied Environmental Science; tillämpad miljövetenskap;

    Sammanfattning : Ecotoxicological test methods are important tools in environmental risk assessment to investigate possible adverse effects that chemical substances may cause to aquatic ecosystems. The main aim of this doctoral thesis was to identify potential toxicity (hazard) of anti-fouling compounds and paints as well as contaminated sediments. LÄS MER

  5. 24. Peat Coated with Iron Oxides : Purification of Metal(loid)-Contaminated Water and Treatment of the Spent Adsorbent

    Författare :Alfreda Kasiuliene; Jurate Kumpiene; Ivan Carabante; Prosun Bhattacharya; Luke Beesly; Luleå tekniska universitet; []
    Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; iron-peat; adsorption; arsenic; metals; combustion; hydrothermal carbonisation; landfilling; Avfallsteknik; Waste Science and Technology;

    Sammanfattning : In Sweden due to the industrial activities, such as wood impregnation, multiple point sources of arsenic (As) contamination in soil and water bodies are scattered over the country. Metals, such as chromium (Cr), copper (Cu), lead (Pb), nickel (Ni), cadmium (Cd) or zinc (Zn) at varying concentrations are usually present as well. LÄS MER

  7. 25. Zinc in folding and misfolding of SOD1 : Implications for ALS

    Författare :Lina Leinartaité; Mikael Oliveberg; Bengt-Harald Jonsson; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; protein stability; protein misfolding; local unfolding; metal binding; energy landscape; protein disease; amyotrophic lateral sclerosis; Biochemistry; biokemi;

    Sammanfattning : Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease causing degeneration of upper and lower motor neurons. Most ALS cases are sporadic; only 6% are associated with mutations in Cu, Zn superoxide dismutase (SOD1). LÄS MER