Sökning: "VP7"

Hittade 5 avhandlingar innehållade ordet VP7.

  1. 1. Folding and retention of rotavirus glycoproteins in the endoplasmic reticulum

    Författare :Ali Mirazimi; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :ER; rotavirus; VP7; NSP4; oligosaccharide processing; N-linked glycosylation; protein disulfide isomerase; calnexin; ATP; ER retention;

    Sammanfattning : The endoplasmic reticulum (ER) is a membrane bound organelle composed of a network of cisternae stretching throughout the cytoplasm. Functionally, the ER performs many essential processes, such as glycosylation, and biosynthesis of lipids; it provides a redox potential condition for forming S-S linkages, and a quality control system, and functions as an intracellular calcium store. LÄS MER

  3. 2. Biochemical and epidemiological characterization of serogroup C rotavirus

    Författare :Mikael Nilsson; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Rotaviruses are classified into seven serogroups (A-G) on the basis of antigenic and genetic properties. Group A rotavirus is the most common cause of diarrhea in infants and young children in both developing and developed countries. LÄS MER

  4. 3. Development and evaluation of a subunit DIVA vaccine against bluetongue virus serotype 8 in cattle

    Författare :Jenna Anderson; Sveriges lantbruksuniversitet; Sveriges lantbruksuniversitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; LANTBRUKSVETENSKAPER; AGRICULTURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; LANTBRUKSVETENSKAPER; AGRICULTURAL SCIENCES;

    Sammanfattning : Bluetongue virus (BTV) causes the primarily vector-borne bluetongue disease of ruminants, which poses a permanent threat to Europe since new serotypes and strains are frequently introduced. Vaccination of cattle is essential to control BTV outbreaks. LÄS MER

  5. 4. Immune responses related to protection against rotavirus after natural infection and vaccination

    Författare :Kari Johansen; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Rotavirus is the most important cause of severe gastroenteritis in children under five years of age and is estimated to be responsible for one-third of all diarrhea-associated hospitalizations and 600,000 deaths/ year worldwide. 1500-1700 rotavirus-associated hospitalizations of children are estimated to occur annually in Sweden (3. LÄS MER

  7. 5. Pediatric rotavirus and norovisrus diarrhea in Nicaragua

    Författare :Filemón Bucardo-Rivera; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Rotavirus; Norovirus; mutations; genetic diversity; host genetic and detection methods;

    Sammanfattning : Diarrheal diseases are still one of the major health problems in developing countries with rotavirus (RV) being the most important pathogen of severe diarrhea in young children. Norovirus (NoV), a common cause of gastroenteritis is now recognized as an important cause of sporadic diarrhea and hospitalization in children worldwide. LÄS MER