Sökning: "activated platelets"

Visar resultat 1 - 5 av 61 avhandlingar innehållade orden activated platelets.

  1. 1. Platelets : intracellular signalling and cellular interaction

    Detta är en avhandling från Linköping : Linköpings universitet

    Författare :Magnus Grenegård; Linköpings universitet.; Linköpings universitet.; [1998]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICINE; MEDICIN;

    Sammanfattning : Activation of platelets is essential to prevent excessive blood loss at the site of vascular injury. These highly reactive cell fragments are also involved in several pathological conditions, in particular arterial thrombosis, which, in the coronary vessels, can lead to reduced blood flow, vessel occlusion and myocardial infarction. LÄS MER

  2. 2. Crosstalk Between Activated Platelets and the Complement System

    Detta är en avhandling från Uppsala : Acta Universitatis Upsaliensis

    Författare :Osama A. Hamad; Uppsala universitet.; [2010]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; platelets; activated platelets; TRAP; chondroitin sulfate; C1q; factor H; C4BP; C3; Compstatin; complement; platelet-leukocyte complexes; platelet microparticles; MEDICINE Microbiology; immunology; infectious diseases Immunology Clinical immunology; MEDICIN Mikrobiologi; immunologi; infektionssjukdomar Immunologi Klinisk immunologi; Klinisk immunologi; Clinical Immunology;

    Sammanfattning : Several studies have shown that complement and thrombotic events co-exist. Platelets have been suspected to act as the bridge between the two cascade systems. LÄS MER

  3. 3. Platelet activation and tissue factor release in hemolytic uremic syndrome

    Detta är en avhandling från Department of Pediatrics, Lund University

    Författare :Anne-lie Ståhl; Lund University.; Lunds universitet.; [2008]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Hemolytic uremic syndrome; platelets; tissue factor; LPS; Shiga toxin; complement system; factor H; clusterin;

    Sammanfattning : Hemolytic uremic syndrome (HUS) is a clinical syndrome characterized by microangiopathic hemolytic anemia, thrombocytopenia and acute renal failure. There are two subtypes: typical HUS associated with enterohemorrhagic E. coli (EHEC) and atypical HUS associated with uninhibited activation of the alternative pathway of complement. LÄS MER

  4. 4. The Plasma Contact System New Functional Insights from a Hemostatic and Thrombotic Perspective

    Detta är en avhandling från Uppsala : Acta Universitatis Upsaliensis

    Författare :Jennie Bäck; Uppsala universitet.; [2011]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Contact activation; factor XII; platelets; coagulation; antithrombin; C1 inhibitor; hemostasis; biomarkers; vascular disease.; Klinisk immunologi; Clinical Immunology;

    Sammanfattning : The physiological role of the plasma contact system still remains a partial enigma. The aim of the presented work was to expand our understanding of the plasma contact system, focusing on its physiological activation and function, principally from a hemostatic perspective. It also explored contact system activation under pathological conditions. LÄS MER

  5. 5. The Role of Histidine-rich Glycoprotein in Angiogenesis and Tumor Growth

    Detta är en avhandling från Uppsala : Acta Universitatis Upsaliensis

    Författare :Åsa Thulin; Uppsala universitet.; [2009]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Histidine-rich glycoprotein; HRG HRGP HPRG; angiogenesis inhibitor; cancer; VEGF; platelets; MEDICINE; MEDICIN; Medicin; Medicine;

    Sammanfattning : Histidine-rich glycoprotein (HRG) is a heparin-binding plasma protein modulating immune, hemostatic and vascular functions. I have studied the antiangiogenic functions of HRG in vitro and in vivo in order to understand the molecular mechanisms of action of HRG as an angiogenesis inhibitor. LÄS MER