Sökning: "platelet microparticles"
Visar resultat 1 - 5 av 24 avhandlingar innehållade orden platelet microparticles.
1. Tissue Factor Biological Functions : Coagulation Activity in Microparticles and Signaling with Focus On Migration and Apoptosis
Sammanfattning : Background: Tissue factor (TF) is a 47 kDa transmembrane glycoprotein known as the main initiator of blood coagulation. TF is over-expressed on many malignant cells and apart from increasing the risk of thrombosis, the presence of TF/FVIIa also promotes the progression of cancer and metastasis by intracellular signaling. LÄS MER
2. Crosstalk Between Activated Platelets and the Complement System
Sammanfattning : Several studies have shown that complement and thrombotic events co-exist. Platelets have been suspected to act as the bridge between the two cascade systems. LÄS MER
3. On the role of neutrophils and NETosis in acute pancreatitis. De neutrophilis NETosique ad pancreatitim acutam pertinentibus
Sammanfattning : .... LÄS MER
4. Vitamin K-dependent protein S - studies of synthesis, structure and function
Sammanfattning : This thesis is based on four projects with the overall aim to investigate vitamin K-dependent protein S functions in relation to its structure. The anticoagulant functions of protein S can be divided in three: 1) cofactor for activated protein C (APC), 2) cofactor for tissue factor pathway inhibitor (TFPI) and 3) APC and TFPI-independent anticoagulant functions. LÄS MER
5. Clinical, epidemiological and molecular aspects of hemolytic uremic syndrome
Sammanfattning : Hemolytic uremic syndrome (HUS) is the most common cause of acute renal failure in children in the western world. HUS is characterized by the triad of hemolytic anemia, thrombocytopenia and renal failure. There are two main subtypes of HUS; typical or D+ (D stands for diarrhea) HUS associated with enterohemorrhagic E. LÄS MER