Sökning: "TBE"

Visar resultat 11 - 15 av 37 avhandlingar innehållade ordet TBE.

  1. 11. Viperin vs. tick-borne encephalitis virus : mechanism of a potent antiviral protein

    Författare :Kirstin Vonderstein; Anna Överby Wernstedt; Magnus Evander; Sonja Best; Umeå universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Tick-borne encephalitis virus; TBEV; type-I interferon; IFN; Interferon-stimulated gene; ISG; viperin; GBF1; CIAO1; antiviral protein; genome replication; particle release; capsid;

    Sammanfattning : Tick-borne encephalitis virus (TBEV) is a very important virus medically, causing mild or severe encephalitis often with long-lasting sequelae. Treatment of tick-borne encephalitis is limited to supportive care, and antiviral drugs are much needed.The type-I interferon (IFN) system is the first line of host defense against many viruses. LÄS MER

  3. 12. Forests and Water - Friends or Foes? : Hydrological implications of deforestation and land degradation in semi-arid Tanzania

    Författare :Klas Sandström; Linköpings universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Water in nature and society; Vatten i natur och samhälle;

    Sammanfattning : This is a study of landscape hydrology; a type of hydrology which focuses on large sca1e implications of hydrologica1 processes as a function of hydroclimate, surface and sub-surface land properties, and the effect of human activities. The focus of the thesis is groundwater recharge and dry season flow following deforestation and land degradation. LÄS MER

  4. 13. Host genetic risk factors to viral diseases - a double-edged sword : Studies of norovirus and tick-borne encephalitis virus

    Författare :Elin Kindberg; Lennart Svensson; Jorma Hinkula; Bertil Lindblom; Tomas Bergström; Linköpings universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Virology; Virologi;

    Sammanfattning : It is today well known that the outcome of a certain infection depends on factors of both the host and the pathogen. Studies of host genetic susceptibility to infectious diseases aim to increase the understanding of why some individuals are more susceptible than others, to a certain infection. LÄS MER

  5. 14. Advancing Endovascular Management of Thoracic Aortic Disease

    Författare :William J. Yoon; Anders Wanhainen; Kevin Mani; Thomas Forbes; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Thoracic endovascular aortic repair; branched thoracic endograft; dissection specific stent graft; computational fluid dynamics; automated image analysis; Kirurgi; Surgery;

    Sammanfattning : Despite technological advances and new endograft designs, endovascular treatment of the thoracic aorta still has important limitations. The aims of this thesis were to obtain further understanding on specific limitations in treating complex thoracic aortic pathologies with current technologies, to gain more insights into the hemodynamic consequences of thoracic endografting, and to explores the potential of deep learning algorithm-based automatic assessment of follow-up CTA imaging. LÄS MER

  7. 15. Transforming growth factor a in human hematopoietic cells

    Författare :Thomas M. Walz; Linköpings universitet; []
    Nyckelord :MEDICINE; MEDICIN;

    Sammanfattning : TGF-a, transforming growth factor a, is a potent growth factor belonging to the family of EGF (epidermal growth factor) -related proteins. Binding to the same receptor as EGF it has a ubiquitous repertoire of target cells, including, mesenchymal, epithelial and neuronal cells. LÄS MER