Sökning: "Surface-exposed protein"

Visar resultat 21 - 25 av 37 avhandlingar innehållade orden Surface-exposed protein.

  1. 21. Mass spectrometry-based proteomic strategies applied to Helicobacter pylori. A Search for candidate vaccine antigens

    Författare :Elisabet Carlsohn; Göteborgs universitet; []
    Nyckelord :proteomics; mass spectrometry; Helicobacter pylori; membrane proteins; nano-liquid chromatography; subcellular fractionation;

    Sammanfattning : This thesis describes the development and refinement of proteomic strategies and the application of these on the human gastric pathogen H. pylori. The purpose was to identify proteins, and in particular membrane proteins, as potential targets for vaccine development. LÄS MER

  3. 22. Structure and Interactions of Human IgG-Fc

    Författare :Daniel Kanmert; Karin Enander; Thomas Skogh; Jonas Wetterö; Sara Snogerup; Linköpings universitet; []
    Nyckelord :NATURAL SCIENCES; NATURVETENSKAP;

    Sammanfattning : This thesis involves structure and interaction studies of the Fc fragment of human IgG. For this purpose, hIgG-Fc of different subclasses were cloned and expressed in the eukaryotic host Pichia pastoris, where relevant protein modification at the post-translational level can be obtained. LÄS MER

  4. 23. Outer membrane proteins of Yersinia pestis : Ail and OmpA

    Författare :Sara Celinda Schesser Bartra; Hans Wolf-Watz; Virginia Miller; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Yersinia pestis; outer membrane proteins; Ail; ompA; Microbiology; immunology; infectious diseases; Mikrobiologi; immunologi; infektionssjukdomar; immunologi; Immunology; mikrobiologi; Microbiology; Infectious Diseases; infektionssjukdomar;

    Sammanfattning : A vast number of studies have been completed on the virulence determinants of Yersinia spp.; however, the focus of many of these studies has been on the virulence plasmid and the plasmid-encoded Type three secretion system. Nevertheless, many chromosomal genes whose products are directly involved in virulence have also been identified. LÄS MER

  5. 24. Porins of Borrelia burgdorferi

    Författare :Marija Pinne; Sven Bergström; Magnus Höök; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Lyme disease; P13; paralog; P66; channel-forming activity; porin; Medical microbiology; Medicinsk mikrobiologi;

    Sammanfattning : Borrelia burgdorferi is a pathogenic spirochete which cycles between its arthropod vector and vertebrate host. If transmitted to humans, B. burgdorferi causes Lyme disease, an infection which can impair different organs, such as the skin, joints, nervous system and heart. LÄS MER

  7. 25. Genetic organization of encapsulated and non-encapsulated Haemophilus influenzae strains. Analysis of the glpTQ and 23S rRNA operons

    Författare :Xin-Ming Song; Malmö Klinisk mikrobiologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Microbiology; intervening sequence; 23S rRNA; transcription; DNA sequence; glpT; Haemophilus influenzae; glpQ; bacteriology; virology; mycology; Mikrobiologi; bakteriologi; virologi; mykologi;

    Sammanfattning : Encapsulated Haemophilus influenzae type b (Hib) and non-encapsulated H. influenzae (NTHi) are important pathogens causing invasive and mucosal infections in children. A 42 kDa surface-exposed lipoprotein, protein D, has been found to be a potential virulence factor of NTHi. LÄS MER