Sökning: "nano-liquid chromatography"

Hittade 4 avhandlingar innehållade orden nano-liquid chromatography.

  1. 1. Mass spectrometry-based proteomic strategies applied to Helicobacter pylori. A Search for candidate vaccine antigens

    Författare :Elisabet Carlsohn; Göteborgs universitet; []
    Nyckelord :proteomics; mass spectrometry; Helicobacter pylori; membrane proteins; nano-liquid chromatography; subcellular fractionation;

    Sammanfattning : This thesis describes the development and refinement of proteomic strategies and the application of these on the human gastric pathogen H. pylori. The purpose was to identify proteins, and in particular membrane proteins, as potential targets for vaccine development. LÄS MER

  3. 2. Mass spectrometry for comparative proteomics of degenerative and regenerative processes in the brain

    Författare :Carina Sihlbom; Göteborgs universitet; []
    Nyckelord :glycoproteomics; quantitative proteomics; glycoprotein; protein quantification; glycosylation; Fourier transform ion cyclotron mass spectrometry; cerebrospinal fluid; Alzheimer s disease; neurodegeneration; neuroregeneration; hippocampus; astrocytes; brain injury; 14-3-3 protein; isoform;

    Sammanfattning : Biological processes involve changes at the protein level. Proteomics aims to determine protein changes from a normal state, to measure for instance recovery or disease progression. Mass spectrometry is the most important tool for identification of proteins and determination of post-translational modifications such as glycosylation. LÄS MER

  4. 3. Lipoproteomics : Environmental and Genetic Factors Affecting High-Density Lipoprotein (HDL)

    Författare :Stefan Ljunggren; Mats Lindahl; Gun Wingren; Helen Karlsson; Jan Albert Kuivenhoven; Björn Dahlbäck; Linköpings universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Sammanfattning : Lipoprotein particles act as lipid transporters in the blood stream, and measuring cholesterol content in specific subclasses of lipoprotein particles has long been, and still is, a frequently used tool to estimate the risk of cardiovascular disease (CVD). High-density lipoprotein (HDL) is a subclass of lipoproteins often regarded as providing protection against CVD via several functions including reverse cholesterol transport and anti-inflammatory capacities. LÄS MER

  5. 4. Immunopeptidomics and autoantigens of interstitial lung diseases

    Författare :Emil Wiklundh; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : We investigate Sarcoidosis and Idiopathic Pulmonary Fibrosis, IPF, to find markers for early fibrosis development. The aetiologies for both diseases are unknown and there is no specific treatment, moreover, there is a lack of diagnostic biomarkers for both diagnose and disease activity. LÄS MER